Results 21 to 30 of about 15,818 (212)
The hierarchical packing of euchromatin domains can be described as multiplicative cascades.
PLoS Computational Biology, 2021 The genome is packed into the cell nucleus in the form of chromatin. Biochemical approaches have revealed that chromatin is packed within domains, which group into larger domains, and so forth.
Amra Noa +4 more
doaj +1 more source
Phosphorylated Lamins in Euchromatin: New Clues to Progeria [PDF]
Developmental Cell, 2020 Lamin proteins not only form the nuclear lamina, but some are also found in the nuclear interior. In this issue of Developmental Cell, Ikegami et al. describe that phosphorylated Lamin C in the nuclear interior interacts with enhancer-like elements and link this to deregulated transcription in progeria.
Bas van Steensel +2 more
openaire +3 more sources
From Effective Interactions Extracted Using Hi-C Data to Chromosome Structures in Conventional and Inverted Nuclei [PDF]
PRX Life 1, 013010 (2023), 2023 Contact probabilities between loci, separated by arbitrary genomic distance, for a number of cell types have been reported using genome-wide chromosome conformation capture (Hi-C) experiments. How to extract the effective interaction energies between active euchromatin (A) and inactive heterochromatin (B) directly from the experimental data, without an
arxiv +1 more source
The Chromatin of Candida albicans Pericentromeres Bears Features of Both Euchromatin and Heterochromatin [PDF]
Frontiers in Microbiology, 2016 Centromeres, sites of kinetochore assembly, are important for chromosome stability and integrity. Most eukaryotes have regional centromeres epigenetically specified by the presence of the histone H3 variant CENP-A. CENP-A chromatin is often surrounded by pericentromeric regions packaged into transcriptionally silent heterochromatin.
Verónica Freire-Benéitez +2 more
openalex +6 more sources
The FUN30 chromatin remodeler, Fft3, protects centromeric and subtelomeric domains from euchromatin formation. [PDF]
PLoS Genetics, 2011 The chromosomes of eukaryotes are organized into structurally and functionally discrete domains. This implies the presence of insulator elements that separate adjacent domains, allowing them to maintain different chromatin structures.
Annelie Strålfors +3 more
doaj +1 more source
Development of Artificial System to Induce Chromatin Loosening in Saccharomyces cerevisiae
Biomolecules, 2022 In eukaryotic cells, loosening of chromatin causes changes in transcription and DNA replication. The artificial conversion of tightly packed chromatin (heterochromatin) to loosely packed chromatin (euchromatin) enables gene expression and regulates cell ...
Ryota Yamamoto +4 more
doaj +1 more source
Scientific Reports, 2021 A characteristic spatial distribution of the main chromatin fractions is observed in most mammalian cell nuclei, with euchromatin localized in the interior and heterochromatin at the nuclear periphery.
Joanna Stachecka +3 more
doaj +1 more source
Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin. [PDF]
PLoS ONE, 2011 H2Av is a versatile histone variant that plays both positive and negative roles in transcription, DNA repair, and chromatin structure in Drosophila.
Zhenhai Zhang, B Franklin Pugh
doaj +1 more source
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective [PDF]
Genome Biology, 2002 Transposable elements are found in the genomes of nearly all eukaryotes. The recent completion of the Release 3 euchromatic genomic sequence of Drosophila melanogaster by the Berkeley Drosophila Genome Project has provided precise sequence for the repetitive elements in the Drosophila euchromatin.
Brent Kronmiller +14 more
openaire +4 more sources
mBio, 2019 Eukaryotic genomes are packaged into chromatin structures that play pivotal roles in regulating all DNA-associated processes. Histone posttranslational modifications modulate chromatin structure and function, leading to rapid regulation of gene ...
Robert Jordan Price +3 more
doaj +1 more source