Results 21 to 30 of about 15,596 (174)
You shall not pass! A Chromatin barrier story in plants
Frontiers in Plant Science, 2022 As in other eukaryotes, the plant genome is functionally organized in two mutually exclusive chromatin fractions, a gene-rich and transcriptionally active euchromatin, and a gene-poor, repeat-rich, and transcriptionally silent heterochromatin.
Florent Velay +3 more
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European Journal of Entomology, 2014 The occurrence of transposable elements (TEs) is a ubiquitous characteristic of eukaryotic genomes, and these sequences are highly abundant in some species. Due to their large genomes, grasshoppers (Orthoptera) appear to be potentially good candidates in
Octavio M. PALACIOS-GIMENEZ +2 more
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A maximum-entropy model to predict 3D structural ensembles of chromatins from pairwise distances: Applications to Interphase Chromosomes and Structural Variants [PDF]
, 2022 The principles that govern the organization of genomes, which are needed for a deeper understanding of how chromosomes are packaged and function in eukaryotic cells, could be deciphered if the three-dimensional (3D) structures are known. Recently, single-cell imaging experiments have determined the 3D coordinates of a number of loci in a chromosome ...
arxiv +1 more source
Molecular Oncology, 2018 Long interspersed nuclear element‐1 (LINE‐1 or L1) reactivation is linked to poor prognosis in non‐small‐cell lung carcinoma (NSCLC), but the molecular bases of this response remain largely unknown.
Pasano Bojang Jr., Kenneth S. Ramos
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gammaH2AX foci form preferentially in euchromatin after ionising-radiation. [PDF]
PLoS ONE, 2007 BACKGROUND:The histone variant histone H2A.X comprises up to 25% of the H2A complement in mammalian cells. It is rapidly phosphorylated following exposure of cells to double-strand break (DSB) inducing agents such as ionising radiation. Within minutes of
Ian G Cowell +5 more
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Involvement of DNA mismatch repair in the maintenance of heterochromatic DNA stability in Saccharomyces cerevisiae. [PDF]
PLoS Genetics, 2017 Heterochromatin contains a significant part of nuclear DNA. Little is known about the mechanisms that govern heterochromatic DNA stability. We show here that in the yeast Saccharomyces cerevisiae (i) DNA mismatch repair (MMR) is required for the ...
Basanta K Dahal +6 more
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A computational model for histone mark propagation reproduces the distribution of heterochromatin in different human cell types [PDF]
PLoS ONE 8(9): e73818, 2013 Chromatin is a highly compact and dynamic nuclear structure that consists of DNA and associated proteins. The main organizational unit is the nucleosome, which consists of a histone octamer with DNA wrapped around it. Histone proteins are implicated in the regulation of eukaryote genes and they carry numerous reversible post-translational modifications
arxiv +1 more source
G3: Genes, Genomes, Genetics, 2018 Satellite DNAs are tandemly repeated sequences clustered within heterochromatin. However, in some cases, such as the major TCAST1 satellite DNA from the beetle Tribolium castaneum, they are found partially dispersed within euchromatin.
Josip Brajković +5 more
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Intra-Chromosomal Potentials from Nucleosomal Positioning Data [PDF]
arXiv, 2021 No systematic method exists to derive intra-chromosomal potentials between nucleosomes along a chromosome consistently across a given genome. Such potentials can yield information on nucleosomal ordering, thermal as well as mechanical properties of chromosomes.
arxiv
Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains
Nature Communications, 2018 Lamina-associated domains (LADs) contact lamins in the nuclear lamina, and lamin B1 was thought to bind heterochromatic regions at the nuclear envelope.
Laura Pascual-Reguant +13 more
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