Results 21 to 30 of about 16,530 (161)
You shall not pass! A Chromatin barrier story in plants
Frontiers in Plant Science, 2022 As in other eukaryotes, the plant genome is functionally organized in two mutually exclusive chromatin fractions, a gene-rich and transcriptionally active euchromatin, and a gene-poor, repeat-rich, and transcriptionally silent heterochromatin.
Florent Velay +3 more
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TALEN outperforms Cas9 in editing heterochromatin target sites
Nature Communications, 2021 While Cas9 outperforms TALENs in euchromatin, it is less efficient in heterochromatic regions. Here the authors, using single-molecule imaging, show that Cas9 uses a less efficient search strategy compared to TALENs in these regions.
Surbhi Jain +12 more
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Molecular Oncology, 2018 Long interspersed nuclear element‐1 (LINE‐1 or L1) reactivation is linked to poor prognosis in non‐small‐cell lung carcinoma (NSCLC), but the molecular bases of this response remain largely unknown.
Pasano Bojang Jr., Kenneth S. Ramos
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Involvement of DNA mismatch repair in the maintenance of heterochromatic DNA stability in Saccharomyces cerevisiae. [PDF]
PLoS Genetics, 2017 Heterochromatin contains a significant part of nuclear DNA. Little is known about the mechanisms that govern heterochromatic DNA stability. We show here that in the yeast Saccharomyces cerevisiae (i) DNA mismatch repair (MMR) is required for the ...
Basanta K Dahal +6 more
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Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains
Nature Communications, 2018 Lamina-associated domains (LADs) contact lamins in the nuclear lamina, and lamin B1 was thought to bind heterochromatic regions at the nuclear envelope.
Laura Pascual-Reguant +13 more
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G3: Genes, Genomes, Genetics, 2018 Satellite DNAs are tandemly repeated sequences clustered within heterochromatin. However, in some cases, such as the major TCAST1 satellite DNA from the beetle Tribolium castaneum, they are found partially dispersed within euchromatin.
Josip Brajković +5 more
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Cell Reports, 2017 RNAi-mediated positive feedback loops are pivotal for the maintenance of heterochromatin, but how they are downregulated at heterochromatin-euchromatin borders is not well understood.
Jan H. Suhren +5 more
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The inheritance of histone modifications depends upon the location in the chromosome in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2011 Histone modifications are important epigenetic features of chromatin that must be replicated faithfully. However, the molecular mechanisms required to duplicate and maintain histone modification patterns in chromatin remain to be determined.
Hiroshi Masumoto +4 more
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Acta Societatis Botanicorum Poloniae, 2014 DNA, NYS and DNFB protein contents were measured cytophotometrically using the Feulgen method in the nuclei of the epidermis from. the basal zone of young leaves and from the basal and apical zones of old leaves in two perennial monocotyledonous species,
Hanna Kuran
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Euchromatin Activity Enhances Segregation and Compaction of Heterochromatin in the Cell Nucleus
Physical Review X, 2022 The large-scale organization of the genome inside the cell nucleus is critical for the cell’s function. Chromatin—the functional form of DNA in cells—serves as a template for active nuclear processes such as transcription, replication, and DNA repair ...
Achal Mahajan +4 more
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