Results 41 to 50 of about 19,515 (233)
Scientific Reports, 2021 A characteristic spatial distribution of the main chromatin fractions is observed in most mammalian cell nuclei, with euchromatin localized in the interior and heterochromatin at the nuclear periphery.
Joanna Stachecka +3 more
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mBio, 2019 Eukaryotic genomes are packaged into chromatin structures that play pivotal roles in regulating all DNA-associated processes. Histone posttranslational modifications modulate chromatin structure and function, leading to rapid regulation of gene ...
Robert Jordan Price +3 more
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Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin. [PDF]
PLoS ONE, 2011 H2Av is a versatile histone variant that plays both positive and negative roles in transcription, DNA repair, and chromatin structure in Drosophila.
Zhenhai Zhang, B Franklin Pugh
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You shall not pass! A Chromatin barrier story in plants
Frontiers in Plant Science, 2022 As in other eukaryotes, the plant genome is functionally organized in two mutually exclusive chromatin fractions, a gene-rich and transcriptionally active euchromatin, and a gene-poor, repeat-rich, and transcriptionally silent heterochromatin.
Florent Velay +3 more
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European Journal of Entomology, 2014 The occurrence of transposable elements (TEs) is a ubiquitous characteristic of eukaryotic genomes, and these sequences are highly abundant in some species. Due to their large genomes, grasshoppers (Orthoptera) appear to be potentially good candidates in
Octavio M. PALACIOS-GIMENEZ +2 more
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TALEN outperforms Cas9 in editing heterochromatin target sites
Nature Communications, 2021 While Cas9 outperforms TALENs in euchromatin, it is less efficient in heterochromatic regions. Here the authors, using single-molecule imaging, show that Cas9 uses a less efficient search strategy compared to TALENs in these regions.
Surbhi Jain +12 more
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Image-based elastography of heterochromatin and euchromatin domains in the deforming cell nucleus
bioRxiv, 2020 Chromatin of the eukaryotic cell nucleus comprises of microscopically dense heterochromatin and loosely packed euchromatin domains, each with distinct transcriptional ability and roles in cellular mechanotransduction.
Soham Ghosh +3 more
semanticscholar +1 more source
Evolutionary History of Alpha Satellite DNA Repeats Dispersed within Human Genome Euchromatin
Genome Biology and Evolution, 2020 Major human alpha satellite DNA repeats are preferentially assembled within (peri)centromeric regions but are also dispersed within euchromatin in the form of clustered or short single repeat arrays.
I. Feliciello +4 more
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Genome Biology, 2020 Background Chromosomes are subdivided spatially to delimit long-range interactions into topologically associating domains (TADs). TADs are often flanked by chromatin insulators and transcription units that may participate in such demarcation. Remarkably,
Alexandre Heurteau +6 more
semanticscholar +1 more source
Molecular Oncology, 2018 Long interspersed nuclear element‐1 (LINE‐1 or L1) reactivation is linked to poor prognosis in non‐small‐cell lung carcinoma (NSCLC), but the molecular bases of this response remain largely unknown.
Pasano Bojang Jr., Kenneth S. Ramos
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