Results 61 to 70 of about 15,596 (174)
Transposable element sequence evolution is influenced by gene context [PDF]
arXiv, 2012 Background: Transposable elements (TEs) in eukaryote genomes are quantitatively the main components affecting genome size, structure and expression. The dynamics of their insertion and deletion depend on diverse factors varying in strength and nature along the genome.
arxiv
Plant, Cell &Environment, EarlyView.ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung +7 more
wiley +1 more source
Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology
CA: A Cancer Journal for Clinicians, EarlyView.Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari +7 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2014 We investigated neuronal self-defense mechanisms in a murine model of amyotrophic lateral sclerosis (ALS), the transgenic hSOD1G93A, during both the asymptomatic and symptomatic stages.
Javier eRiancho +5 more
doaj +1 more source
Landscape of rare‐allele variants in cultivated and wild soybean genomes
The Plant Genome, Volume 18, Issue 2, June 2025.Abstract Rare‐allele variants are important for crop improvement because they can be linked to important traits. However, genome‐wide distribution and annotation of rare‐allele variants have not been reported. We analyzed sequencing data from 1556 soybean accessions and found 6,533,419 rare‐allele variants in Glycine max and 941,274 in Glycine soja ...
Zhi Liu +9 more
wiley +1 more source
Manipulation of RNA polymerase III by Herpes Simplex Virus-1
Nature Communications, 2022 RNA Polymerase III (Pol III) transcribes non-coding RNA, including tRNAs. Applying different RNA-Seq techniques, Dremel et al. provide the Pol III transcriptional landscape of Herpes simplex virus 1 (HSV-1) infected cells.
Sarah E. Dremel +4 more
doaj +1 more source
Medicinal Research Reviews, Volume 45, Issue 3, Page 985-1015, May 2025.ABSTRACT This review provides a comprehensive overview of the role of G9a/EHMT2, focusing on its structure and exploring the impact of its pharmacological and/or gene inhibition in various neurological diseases. In addition, we delve into the advancements in the design and synthesis of G9a/EHMT2 inhibitors, which hold promise not only as a treatment ...
Aina Bellver‐Sanchis +10 more
wiley +1 more source
Mg 2+ -dependent ATPase activity in triatomine salivary glands (Heteroptera, Triatominae)
Iheringia: Série Zoologia, 2017 Mg2+-ATPase activity was detected in the three salivary glands of adult triatomines, males and females, of Triatoma infestans (Klug, 1834) and Panstrongylus megistus (Burmeister, 1835) (Heteroptera, Triatominae). A predominance of binucleated cells in D1
Ana C. B. M. Anhê +1 more
doaj +1 more source
3D Mechanical Confinement Directs Muscle Stem Cell Fate and Function
Advanced Biology, Volume 9, Issue 4, April 2025.This study reveals that the physical environment surrounding muscle stem cells (MuSCs) plays a crucial role in their function. Using a 3D hydrogel system, it shows that increased confinement preserves MuSC stemness by limiting activation, proliferation, and differentiation.
GaYoung Park +3 more
wiley +1 more source
Advanced Science, Volume 12, Issue 14, April 10, 2025.This study elucidates the mechanism underlying LINC01235 promotes clonal evolution and selection under treatment pressure by facilitating DNA replication licensing and CIN, leading to increased therapeutic resistance in HER2+ breast cancer. Targeting LINC01235‐related pathways with ATR inhibitors may be a viable strategy for clinical application ...
Qi Zhang +18 more
wiley +1 more source