Results 81 to 90 of about 19,515 (233)

Dynamic replacement of histone H3 variants reprograms epigenetic marks in early mouse embryos. [PDF]

PLoS Genetics, 2011
Upon fertilization, reprogramming of gene expression is required for embryo development. This step is marked by DNA demethylation and changes in histone variant composition.
Tomohiko Akiyama, Osamu Suzuki, Junichiro Matsuda, Fugaku Aoki   +3 more
doaj   +1 more source

Interaction of TFAP2A with the Ku70/80 complex is crucial for HIF‐dependent activation of hypoxia‐inducible genes

The FEBS Journal, EarlyView.
Under normoxic conditions, the SUMOylated fraction of TFAP2A cannot interact with the Ku70/Ku80 complex, nor it can bind to chromatin. The unSUMOylated fraction pre‐occupies the chromatin of a subset of hypoxia‐induced genes together with the Ku70/Ku80 complex for basal euchromatin formation. Under hypoxic conditions, the SUMOylation equilibrium shifts
Amalia Kanoura, Antonis Giakountis, Chrysa Filippopoulou, Angeliki Karagiota, George Stamatakis, Martina Samiotaki, George Panayotou, George Simos, Georgia Chachami   +8 more
wiley   +1 more source

Chromatin associations in Arabidopsis interphase nuclei

Frontiers in Genetics, 2014
The arrangement of chromatin within interphase nuclei seems to be caused by topological constraints and related to gene expression depending on tissue and developmental stage.
Veit eSchubert, Radek eRudnik, Ingo eSchubert   +2 more
doaj   +1 more source

A new piece in the repeatome puzzle of Triatominae bugs: The analysis of Triatoma rubrofasciata reveals the role of satellite DNAs in the karyotypic evolution of distinct lineages

Insect Molecular Biology, EarlyView.
Satellite DNAs comprise the major component of the Triatoma rubrofasciata repeatome, highlighting their central role in genome composition and architecture. Satellite DNA families show recent amplification in heterochromatin and older, more divergent satellite DNAs located in euchromatin, indicating distinct evolutionary histories.
Sebastián Pita, Pablo Mora, José M. Rico‐Porras, Diogo C. Cabral‐de‐Mello, Francisco J. Ruiz‐Ruano, Teresa Palomeque, Ho Viet Hieu, Francisco Panzera, Pedro Lorite   +8 more
wiley   +1 more source

SUMO-targeted ubiquitin ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin

Molecular Biology of the Cell, 2016
A new posttranslational modification is found of centromeric histone H3 variant Cse4. Cse4 is sumoylated by E3 ligases Siz1 and Siz2 and ubiquitinated by Slx5, a Sumo-targeted ubiquitin ligase.
Kentaro Ohkuni, Yoshimitsu Takahashi, Alyona Fulp, Josh Lawrimore, W. Au, Nagesh Pasupala, Reuben Levy-Myers, Jack Warren, A. Strunnikov, R. Baker, O. Kerscher, K. Bloom, M. Basrai   +12 more
semanticscholar   +1 more source

Optimisation of freeze substitution protocols for the examination of malaria parasite structure by volumetric electron microscopy

Journal of Microscopy, EarlyView.
Abstract Malaria is one of the deadliest infectious diseases in the world, annually responsible for over 400,000 deaths. It is caused by parasites of the genus Plasmodium, which undergo remarkable structural changes during their development within different cells across various hosts.
Rachel Rachid, Camila Wendt, Wanderley de Souza, Kildare Miranda   +3 more
wiley   +1 more source

Mg 2+ -dependent ATPase activity in triatomine salivary glands (Heteroptera, Triatominae)

Iheringia: Série Zoologia, 2017
Mg2+-ATPase activity was detected in the three salivary glands of adult triatomines, males and females, of Triatoma infestans (Klug, 1834) and Panstrongylus megistus (Burmeister, 1835) (Heteroptera, Triatominae). A predominance of binucleated cells in D1
Ana C. B. M. Anhê, Maria T. V. Azeredo-Oliveira   +1 more
doaj   +1 more source

Entropic effect of macromolecular crowding enhances binding between nucleosome clutches in heterochromatin, but not in euchromatin

Scientific Reports, 2018
Sharp increase in macromolecular crowding induces abnormal chromatin compaction in the cell nucleus, suggesting its non-negligible impact on chromatin structure and function. However, the details of the crowding-induced chromatin compaction remain poorly
Inrok Oh, Saehyun Choi, YounJoon Jung, Jun Soo Kim   +3 more
semanticscholar   +1 more source

DNA Hypomethylation Is One of the Epigenetic Mechanisms Involved in Salt‐Stress Priming in Soybean Seedlings

Plant, Cell &Environment, EarlyView.
ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung, Qianwen Wang, Long‐Yiu Chan, Zhili Wang, Mingkun Huang, Man‐Wah Li, Fuk‐Ling Wong, Hon‐Ming Lam   +7 more
wiley   +1 more source

Mapping of the juxtacentromeric heterochromatin-euchromatin frontier of human chromosome 21 [PDF]

Genome Research, 2006
Euchromatin and heterochromatin are functional compartments of the genome. However, little is known about the structure and the precise location of the heterochromatin–euchromatin boundaries in higher eukaryotes. Constitutive heterochromatin in centromeric regions is associated with (1) specific histone methylation patterns, (2) high levels of DNA ...
Grunau, Christoph, Buard, J., Brun, Me, de Sario, Albertina   +3 more
openaire   +3 more sources