Results 61 to 70 of about 54,279 (213)
Advanced Science, EarlyView.ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
Eliciting the Functional Taxonomy from protein annotations and taxa [PDF]
, 2016 The advances of omics technologies have triggered the production of an enormous volume of data coming from thousands of species. Meanwhile, joint international efforts like the Gene Ontology (GO) consortium have worked to provide functional information ...
Berselli, Michele +6 more
core +2 more sources
An Unfolding Story: AlphaFold's View on Protein Flexibility
Helvetica Chimica Acta, EarlyView.AlphaFold confidence measures allow for detailed proteome‐wide characterization of protein flexibility. All flexibility measures increased substantially in the evolutionary transition from prokaryota to eukaryota. ABSTRACT The AlphaFold confidence measures are related to conformation distribution of the protein.
Gunnar Jeschke
wiley +1 more source
PLoS ONE, 2015 Phylogenetic profiling, a network inference method based on gene inheritance profiles, has been widely used to construct functional gene networks in microbes. However, its utility for network inference in higher eukaryotes has been limited.
Junha Shin, Insuk Lee
doaj +1 more source
Chrysophanol: A Natural Anthraquinone with Multifaceted Biotherapeutic Potential
Biomolecules, 2019 Chrysophanol is a unique anthraquinone having broad-spectrum therapeutic potential along with ecological importance. It is the first polyketide that has been reported to be biosynthesized in an organism-specific manner. The traditional Chinese and Korean
Prateeksha +9 more
doaj +1 more source
Metaxa : a software tool for automated detection and discrimination among ribosomal small subunit (12S/16S/18S) sequences of archaea, bacteria, eukaryotes, mitochondria, and chloroplasts in metagenomes and environmental sequencing datasets [PDF]
, 2011 Peer ...
Abarenkov, Kessy +9 more
core +1 more source
SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies
PROTEOMICS, EarlyView.ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà +10 more
wiley +1 more source
An extra dimension in protein tagging by quantifying universal proteotypic peptides using targeted proteomics [PDF]
, 2016 The use of protein tagging to facilitate detailed characterization of target proteins has not only revolutionized cell biology, but also enabled biochemical analysis through efficient recovery of the protein complexes wherein the tagged proteins reside ...
De Sutter, Delphine +9 more
core +2 more sources
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo +5 more
wiley +1 more source
BMC Microbiology, 2017 Background Representatives of the genus Bacillus are increasingly used in agriculture to promote plant growth and to protect against plant pathogens. Unfortunately, hitherto the impact of Bacillus inoculants on the indigenous plant microbiota has been ...
Junqing Qiao +5 more
doaj +1 more source