Results 211 to 220 of about 443,960 (348)

Early photosynthetic eukaryotes inhabited low-salinity habitats

Proceedings of the National Academy of Sciences of the United States of America, 2017
P. Sánchez‐Baracaldo, J. Raven, D. Pisani, A. Knoll   +3 more
semanticscholar   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

Mapping life's disparity and evolutionary constraints in a geometric complexity space. [PDF]

Sci Adv
Dera G, Nardin E, Risser L, Albino M, Garnier Q, Kardacz M, Monge-Waleryszak L.   +6 more
europepmc   +1 more source

Improved software detection and extraction of ITS1 and ITS2 from ribosomal ITS sequences of fungi and other eukaryotes for analysis of environmental sequencing data

, 2013
J. Bengtsson-Palme, Martin Ryberg, M. Hartmann, S. Branco, Z. Wang, Anna Godhe, P. Wit, M. Sánchez-García, I. Ebersberger, F. Sousa, A. Amend, A. Jumpponen, M. Unterseher, E. Kristiansson, K. Abarenkov, Y. Bertrand, Kemal Sanli, K. M. Eriksson, Unni Vik, Vilmar Veldre, R. Nilsson   +20 more
semanticscholar   +1 more source

Translation Elongation and Recoding in Eukaryotes.

Cold Spring Harbor Perspectives in Biology, 2018
T. Dever, J. Dinman, R. Green
semanticscholar   +1 more source

Preservation of Complex Multiphase Architectures in Polymer‐Based Artificial Cells by Photo‐Crosslinking

Advanced Science, EarlyView.
Phase separation organizes cellular components, yet stabilizing such dynamic structures in artificial cells remains challenging. A photo‐crosslinking approach is presented that prolongs the lifetime of different structures in coacervate‐based artificial cells while maintaining dynamic formation.
Madelief A. M. Verwiel, Alexander B. Cook, Yiǧitcan Sümbelli, Nadia A. Erkamp, Jan C. M. van Hest   +4 more
wiley   +1 more source

G-protein-coupled receptor diversity and evolution in the closest living relatives of metazoa. [PDF]

Elife
Garcia De Las Bayonas A, King N.
europepmc   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Eukaryogenesis From FECA to LECA: Radical Steps Along the Way. [PDF]

Bioessays
Speijer D.
europepmc   +1 more source

A general method for isolation of high molecular weight DNA from eukaryotes.

Nucleic Acids Research, 1976
N. Blin, D. Stafford
semanticscholar   +1 more source