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Eukaryotic DNA Polymerases

Annual Review of Biochemistry, 2002
▪ Abstract  Any living cell is faced with the fundamental task of keeping the genome intact in order to develop in an organized manner, to function in a complex environment, to divide at the right time, and to die when it is appropriate. To achieve this goal, an efficient machinery is required to maintain the genetic information encoded in DNA during ...
Hubscher U, Maga G, Spadari S
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Eukaryotic Phospholipid Biosynthesis

Annual Review of Biochemistry, 1995
The current status of the biochemistry of phospholipid biosynthesis is presented. The review focuses on the identification and characterization of molecular tools such as purified enzymes and cloned genes and cDNAs for those enzymes. The enzymes discussed are those involved in the biosynthesis of the major phospholipid classes, namely, phosphatidate ...
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Eukaryotic DNA Replication

Annual Review of Biochemistry, 1986
ADENOVIRUS 736 Genome Structure and Replication Mode 736 In Vitro Replication 736 SV40 DNA REPLICATION 739 The Role ofT Antigen in Initiation . 740 DNA Sequences Required for Replication 742 In Vitro Replication Systems 744 Proteins Required/or SV40 DNA Replication In Vitro 745 DNA Sequences Required 746 Minimal Origins Used In Vitro
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Single-Molecule Localization Microscopy in Eukaryotes

Chemical Reviews, 2017
Markus Sauer, Mike Heilemann
exaly   +2 more sources

Eukaryotic DNA Replication

Critical Reviews in Biochemistry and Molecular Biology, 1992
The past decade has witnessed an exciting evolution in our understanding of eukaryotic DNA replication at the molecular level. Progress has been particularly rapid within the last few years due to the convergence of research on a variety of cell types, from yeast to human, encompassing disciplines ranging from clinical immunology to the molecular ...
A G, So, K M, Downey
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Eukaryotic DNA primase

Trends in Biochemical Sciences, 2000
Eukaryotic DNA primase initiates the synthesis of all new DNA strands by synthesizing short RNA oligomers on single-stranded DNA. Additionally, primase helps couple replication and repair and is critical for telomere maintenance and, therefore, chromosome stability.
B, Arezi, R D, Kuchta
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The molecular basis of translation initiation and its regulation in eukaryotes

Nature reviews. Molecular cell biology, 2023
J. Brito Querido   +2 more
semanticscholar   +1 more source

Eukaryotic DNA polymerases

Current Opinion in Structural Biology, 2018
The eukaryotic DNA replication machinery is conserved from yeast to humans and requires the actions of multiple DNA polymerases. In addition to replicative DNA polymerases for duplication of the leading and lagging DNA strands, another group of specialized polymerases is required for DNA repair and/or translesion DNA synthesis (TLS).
Rinku, Jain   +2 more
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Microbial Eukaryote Globins

2013
A bioinformatics survey of about 120 protist and 240 fungal genomes and transcriptomes revealed a broad array of globins, representing five of the eight subfamilies identified in bacteria. Most conspicuous is the absence of protoglobins and globin-coupled sensors, except for a two-domain globin in Leishmanias, that comprises a nucleotidyl cyclase ...
Serge N, Vinogradov   +5 more
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Eukaryotic DNA methylation

Human Genetics, 1983
Eukaryotic genomes contain 5-methylcytosine (5mC) as a rare base.5mC arises by postsynthetic modification of cytosine and occurs, at least in animals, predominantly in the dinucleotide CpG. The base is not distributed randomly in these genomes but conforms to a pattern. This pattern varies between taxa but appears to be inherited in a semi-conservative
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