Results 151 to 160 of about 387,698 (305)

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Pathogenicity of Plesiomonas shigelloides : interactions with eukaryotic host cells in vitro [PDF]

open access: yes, 2003
Diarrhoea is one of the leading causes of morbidity and mortality in\ud populations in developing countries and is a significant health issue\ud throughout the world.
Theodoropoulos, Christina
core  

Cytotoxic and mutagenic effects of the food additive tartrazine on eukaryotic cells. [PDF]

open access: yesBMC Pharmacol Toxicol, 2022
Dos Santos JR   +17 more
europepmc   +1 more source

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao   +14 more
wiley   +1 more source

Orthologous grouping and comparison of prokaryotic and eukaryotic EV proteomes [PDF]

open access: yes, 2019
Introduction: Most prokaryotic and eukaryotic cells secrete Extracellular vesicles (EVs) with bioactive molecules, including proteins and nucleic acid.
LEE, JAEWOOK   +4 more
core  

TiO2 Nanoparticles and Their Effects on Eukaryotic Cells: A Double-Edged Sword. [PDF]

open access: yesInt J Mol Sci, 2022
Gojznikar J   +4 more
europepmc   +1 more source

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

open access: yesAdvanced Science, EarlyView.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu   +7 more
wiley   +1 more source

eIF3j inhibits translation of a subset of circular RNAs in eukaryotic cells. [PDF]

open access: yesNucleic Acids Res, 2022
Song Z   +7 more
europepmc   +1 more source

EUKARYOTIC CELL [PDF]

open access: yesEukaryotic Cell, 2006
openaire   +1 more source

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