Results 291 to 300 of about 604,841 (328)

Learning to Navigate in Chemical Fields Without A Map at Low Reynolds Numbers

Advanced Science, EarlyView.
Deep reinforcement learning enables a reconfigurable artificial microswimmer to exhibit run‐and‐tumble strategy to navigate toward a chemical source. This mapless microswimmer can robustly navigate in diverse chemical fields without relying on a pre‐existing map.
Yangzhe Liu, On Shun Pak, Alan C. H. Tsang   +2 more
wiley   +1 more source

CDK4/6 Inhibitor Priming Enhances PD‐1 Blockade via Sellhi Neutrophil‐Induced Stat5a+ Progenitor Exhausted CD8+ T Cell

Advanced Science, EarlyView.
Activated tumor‐intrinsic cyclin D1‐CDK4/6 signaling attenuates lymphocyte infiltration, and consequently, and immunotherapy resistance in HNSCC. It is discovered that brief CDK4/6i priming before anti‐PD‐1 results in enhanced durability of ICB response durability through Stat5a+ progenitor exhausted CD8+ T cells induced by IL15‐secreted Sell(hi ...
Yu Zhang, Bao Sun, Rong Zhou, Zizhen Gong, Yong Han, Wenjie Tao, Chaoji Shi, Wuchang Zhang, Laikui Liu, Zhiyuan Zhang, Jiang Li, Qi Zhu, Weiwen Zhu, Ziyue Gu   +13 more
wiley   +1 more source

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Proteodynamics and aging of eukaryotic cells

Mechanisms of Ageing and Development, 2021
All aspects of each protein existence in the eukaryotic cells, starting from the pre-translation events, through translation, multiple different post-translational modifications, functional life and eventual proteostatic removal after loss of functionality and changes in physico-chemical properties, can be collectively called the proteodynamics.
Jacek M. Witkowski, Tamas Fulop, Ewa Bryl   +2 more
openaire   +3 more sources

Phages in eukaryotic cells

Folia Microbiologica, 1985
Urine from a patient after kidney transplantation added to a human embryonic lung culture caused the appearance of dark spots shown to contain cells with phages resembling group A, as well as bodies resembling Chlamydiae.
I. Trebichavský, V. Štěpánová, M. Koukal, J. Horáček   +3 more
openaire   +3 more sources

The origin of the eukaryotic cell

Trends in Biochemical Sciences, 1996
Molecular sequence data are beginning to provide important insights into the evolutionary origin of eukaryotic cells. Global phylogenies of numerous protein sequences indicate that the eukaryotic cell nucleus is a chimera, which has received major contributions from both a Gram-negative eubacterium and an archaebacterium.
G. Brian Golding, Radhey S. Gupta
openaire   +3 more sources

DNA‐Modification of Eukaryotic Cells

Small, 2012
AbstractA novel bioorthogonal method for the modification of cells with single‐stranded DNA oligomers is compared to five alternative methods with respect to labeling efficacy, specificity, and effects on cell viability. The new method is based on oxime ligation of aminooxybiotin to aldehyde groups installed by periodate cleavage of cell‐surface ...
Christof M. Niemeyer, Christof M. Niemeyer, Hendrik Schroeder, Hendrik Schroeder, Maximilian Glettenberg, Katrin Vogel   +5 more
openaire   +4 more sources

Apoptosis in cryopreserved eukaryotic cells

Biochemistry (Moscow), 2016
This review considers apoptosis mechanisms that have been revealed in cryopreserved cells and which can be controlled using different chemical agents, thereby improving the viability of cells after their return to normal conditions. The role of oxidative stress as of the most significant damaging factor is discussed, as well as the reasonability of ...
M. A. Savitskaya, G. E. Onishchenko
openaire   +3 more sources

Hybridization of Eukaryotic Cells

Annual Review of Microbiology, 1973
CHROMOSOME BEHAVIOR IN HYBRID CELLS . ...... 191 Intraspecific Crosses ........
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Eukaryotic Cell–Cell Fusion Families

2011
Abstract The capacity of cells to unite in a regulated fashion, through fusion of their plasma membranes, is essential for reproduction and development in eukaryotes. Yet, the majority of proteins that mediate this process (i.e. fusogens) remain unidentified or uncharacterized.
Ori Avinoam, Benjamin Podbilewicz
openaire   +3 more sources

Regulation of the Cell Cycle in Eukaryotic Cells

1981
Publisher Summary This chapter examines several models and mechanisms that are proposed to describe the regulation of the cell cycle in eukaryotic cells. It discusses how cell growth is coordinated with cell division and how entry into S phase is controlled in cycling cells.
Rosalind M. Yanishevsky, Gretchen H. Stein   +1 more
openaire   +3 more sources