Results 131 to 140 of about 106,156 (238)

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2–7 onto DNA [PDF]

, 2014
Stefan A. Samel, Alejandra Fernandez‐Cid, Jingchuan Sun, Alberto Riera, Silvia Tognetti, M. Carmen Herrera, Huilin Li, Christian Speck   +7 more
openalex   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

Advanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha, Kyle L. MacQuarrie, Marcelo Carignano, Cody L. Dunton, Ruyi Gong, Joe Ibarra, Lucas M. Carter, Wing Shun Li, Rikkert Nap, Parambir S. Dulai, Igal Szleifer, Vadim Backman   +11 more
wiley   +1 more source

Archaeology of eukaryotic DNA replication. [PDF]

Cold Spring Harb Perspect Biol, 2013
Makarova KS, Koonin EV.
europepmc   +1 more source

Initiation of chromosomal DNA replication in eukaryotic cells; contribution of yeast genetics to the elucidation

, 2011
Hiroyuki Araki
openalex   +2 more sources

Kinetic Model of DNA Replication in Eukaryotic Organisms [PDF]

, 2002
John H. Herrick, Suckjoon Jun, John Bechhoefer, Aaron Bensimon   +3 more
openalex   +1 more source

Lactate Metabolic Reprogramming Mediated by CircRNA–LDHA Complex Facilitates Innate Immune Evasion of Liver Cancer

Advanced Science, EarlyView.
CircSMPD4 physically combines with lactate dehydrogenase A (LDHA) and reduces its acetylation level via SIRT2‐dependent deacetylation, thereby inhibiting chaperone‐mediated autophagy‐lysosome degradation of LDHA. Upregulating LDHA leads to increasing lactate production and extracellular export, which in turn suppresses natural killer cell cytotoxicity ...
Hao Shen, Boqiang Liu, Jing He, Weijun Zhao, Weiqi Li, Lingfeng Ma, Lidan Hou, Yi Wang, Chenqi Jin, Yushun Chang, Jie Lin, Jia Zhao, Binghan Jin, Yuanshi Tian, Xiujun Cai, Liang Shi, Yifan Wang   +16 more
wiley   +1 more source

Processing ribonucleotides incorporated during eukaryotic DNA replication. [PDF]

Nat Rev Mol Cell Biol, 2016
Williams JS, Lujan SA, Kunkel TA.
europepmc   +1 more source

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen [PDF]

, 1995
Xiangyang Li, Jun Li, John Harrington, Michael R. Lieber, Peter Burgers   +4 more
openalex   +1 more source

Soil Nutrient Enrichment Induces Trade‐Offs in Bacterial Life‐History Strategies Promoting Plant Productivity

Advanced Science, EarlyView.
Soil nutrient enrichment induces the trade‐offs between bacterial functional potential and growth‐rate potential. Such trade‐offs favor specific plant‐beneficial species and genes, playing a pivotal role in determining plant productivity. These findings enhance the understanding of the microbial responses in agroecosystems to ongoing global ...
Yuanyuan Yan, Xing Zhou, Liangliang Liu, Zucong Cai, Josep Penuelas, Xinqi Huang   +5 more
wiley   +1 more source

Replication Protein A, the Main Eukaryotic Single-Stranded DNA Binding Protein, a Focal Point in Cellular DNA Metabolism [PDF]

Heinz‐Peter Nasheuer, Anna Marie Meaney, Timothy Hulshoff, Ines Thiele, Nichodemus O. Onwubiko   +4 more
openalex   +1 more source