Results 141 to 150 of about 106,156 (238)

Uncoupling of Sister Replisomes during Eukaryotic DNA Replication [PDF]

, 2010
Hasan Yardimci, A.B. Loveland, Satoshi Habuchi, Antoine M. van Oijen, Johannes C. Walter   +4 more
openalex   +1 more source

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

Advanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li, Deqiang Kong, Hongmei Liu, Jie Yang, Jiale Zhou, Yuqiang Qian, Ding Zhao, Jinze Li, Xinyu Wu, Tao Zhang, Xiaodi Sun, Yang Han, Liangxue Lai, Zhanjun Li   +13 more
wiley   +1 more source

Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development. [PDF]

DNA Repair (Amst), 2017
Shima N, Pederson KD.
europepmc   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

Advanced Science, EarlyView.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu, Guigen Zhang, Yuan Lin, Shiming Yi, Jingyu Yang, Xueying Lin, Deli Song, Zhiheng Liu, Jiayu Zhang, Ying Zeng, Shanyu Huang, Zhen Fan, Jifu Zhang, Ying Liu, Cheng Hu, Wenbo Zhu, Wei Yin, Jun Hu, Guangmei Yan, Jing Cai, Jiankai Liang   +20 more
wiley   +1 more source

Relationship of eukaryotic DNA replication to committed gene expression: general theory for gene control. [PDF]

, 1991
Luis P. Villarreal
openalex   +2 more sources

Regulated eukaryotic DNA replication origin firing with purified proteins. [PDF]

Nature, 2015
Yeeles JT, Deegan TD, Janska A, Early A, Diffley JF.   +4 more
europepmc   +1 more source

ACE‐mediated Glycosylation Stabilizes PSAP To Promote GPR37‐dependent Macrophage‐Nucleus Pulposus Cells Crosstalk and TGFβ Signaling in Alleviating Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ACE can modulate the CBL‐mediated K48 ubiquitination degradation of PSAP by altering its glycosylation levels in NP cells. As a result, NP cells secrete PSAP, which interacts with GPR37 on macrophage surfaces, facilitating their polarization toward the M2 phenotype. These M2 macrophages subsequently secrete TGFβ, which exerts feedback effects on the NP
Youfeng Guo, Feng Wang, Bijun Wang, Yu Zhou, Chao Wang, Tao Hu, Desheng Wu   +6 more
wiley   +1 more source

How MCM loading and spreading specify eukaryotic DNA replication initiation sites. [PDF]

F1000Res, 2016
Hyrien O.
europepmc   +1 more source

Eukaryotic DNA replication: Orchestrated action of multi-subunit protein complexes

, 2017
Sukhyun Kang, Mi-Sun Kang, Eunjin Ryu, Kyungjae Myung   +3 more
openalex   +2 more sources

Roles of phosphatases in eukaryotic DNA replication initiation control

, 2022
Fiona Jenkinson, Philip Zegerman
openalex   +1 more source