Results 191 to 200 of about 204,342 (301)

Prokaryotic defense systems: Diversity and evolutionary adaptation. [PDF]

mLife
Yang C, Gong L, Guo J, Xiang H.
europepmc   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

Asgard archaea: have we found our microbial ancestors? [PDF]

EMBO J
Schleper C, Rodrigues-Oliveira T.
europepmc   +1 more source

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Giant DNA viruses encode a hallmark translation initiation complex of eukaryotic life. [PDF]

Cell
Fels JM, Hill AB, Han R, Garcia JM, Bisio H, Abergel C, Kranzusch PJ, Lee ASY.   +7 more
europepmc   +1 more source

Biochar‐Induced Shifts in Fungal Community Structure and Their Association With Soil Physical Properties in Degraded Soil From the Brazilian Semiarid

Land Degradation &Development, EarlyView.
ABSTRACT Soil degradation compromises ecosystem functioning. Biochar, a carbon‐rich amendment, has gained attention as a promising strategy to enhance soil structure and restore microbial balance. This study investigated the effects of two biochars, cashew bagasse biochar (CBB) and a co‐pyrolyzed biochar produced from sewage sludge and cashew pruning ...
João Marcos Rodrigues dos Santos, Arthur Prudêncio de Araujo Pereira, Kaio Gráculo Vieira Garcia, Ícaro Vasconcelos do Nascimento, Francisco Luan Almeida Barbosa, Tiago da Costa Dantas Moniz, Gilvanete da Silva Henrique, Murilo de Sousa Almeida, Vania Maria Maciel Melo, Mirian Cristina Gomes Costa, Helon Hébano de Freitas Sousa, Adriana Guirado Artur, Christiana de Fátima Bruce da Silva, Odair Pastor Ferreira, Antônio Gomes de Souza Filho, Erika Valente de Medeiros, Ademir Sergio Ferreira Araujo, Rafael Santiago da Costa, Jaedson Cláudio Anunciato Mota   +18 more
wiley   +1 more source

License to Replicate: Mechanisms of Licensing Eukaryotic Origins for DNA Replication. [PDF]

Bioessays
Frisbie V, Bleichert F.
europepmc   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

DNA translocation by the CMG helicase: the helical inchworm model. [PDF]

Biochem Soc Trans
Batra S, Allwein B, Wang YL, Hite RK, Remus D.   +4 more
europepmc   +1 more source

Quality control in the initiation of eukaryotic DNA replication. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2011
Diffley JF.
europepmc   +1 more source