Results 221 to 230 of about 206,173 (282)

Comparative Analysis of Heat Exposure‐Induced Molecular Changes in Two Turtle Species with Contrasting Thermal Adaptations

Integrative Zoology, EarlyView.
Protein processing in the endoplasmic reticulum is highlighted in response to heat stress in Platysternon megacephalum. Under heat stress, the up‐regulation of genes such as CHOP in protein processing in the endoplasmic reticulum pathway, along with the suppression of energy and lipid metabolism and the up‐regulation of JARID2 expression, leads to ...
Jian Hong, Yangchun Gao, Jiaxuan Li, Yan Ge, Yufeng Wei, Youqiang Yin, Qianru Liang, Shiping Gong   +7 more
wiley   +1 more source

Interplay Between DNA Polymerase, RNA Polymerase, and RNase H1 During Head-On Transcription-Replication Conflict. [PDF]

Int J Mol Sci
Timofeyeva NA, Tsoi EI, Novopashina DS, Kuznetsov NA, Kuznetsova AA.   +4 more
europepmc   +1 more source

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

Integrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li, Congcong Qiao, Xiujuan Li, Maolin Huang, Zhenlong Wang, Luye Shi   +5 more
wiley   +1 more source

The GHKL ATPase Family as a Paradigm for MutL Homolog Function in DNA Mismatch Repair. [PDF]

Int J Mol Sci
Piscitelli JM, Manhart CM.
europepmc   +1 more source

A review of autonomous reef monitoring structures (ARMS) for monitoring hard‐bottom benthic biodiversity

Methods in Ecology and Evolution, EarlyView.
Abstract Amid increasing anthropogenic pressures on ecosystems, standardised biodiversity monitoring is critical for assessing biodiversity change. Marine hard‐bottom habitats, though ubiquitous and biodiverse, present challenges for biodiversity monitoring due to their complex structure and limited accessibility. Autonomous reef monitoring structures (
Aaron Jessop, Margaux Steyaert, Nauras Daraghmeh, Justine Pagnier, Melody S. Clark, Lloyd S. Peck, Keiron P. P. Fraser   +6 more
wiley   +1 more source

Skin Lipid–Microbe Interplay Links Staphylococcus hominis to Barrier Control in Adult Atopic Dermatitis

Allergy, EarlyView.
This study investigates mutual interaction of skin microbes and surface lipids in AD using the advanced method of shotgun lipidomics with ultra‐broad coverage of lipids and 16S amplicon sequencing of tape strips taken from lesional and non‐lesional AD and healthy controls.
Madhumita Bhattacharyya, Felix Lauffer, Manja Jargosch, Kristina Frey, Mahsa Shahidi Dadras, Theresa Raunegger, Sophia Wasserer, Carsten B. Schmidt‐Weber, Tilo Biedermann, Kilian Eyerich, Stefanie Eyerich, Claudia Traidl‐Hoffmann, Christian Klose, Matthias Reiger, Natalie Garzorz‐Stark   +14 more
wiley   +1 more source

Identification of Cdc45-interacting partners uncovers two Leishmania donovani proteins involved in DNA replication. [PDF]

BMC Microbiol
Dashora V, Singh A, Pandey A, Saha S.
europepmc   +1 more source

Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis

Acta Ophthalmologica, EarlyView.
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Anders Ivarsen   +5 more
wiley   +1 more source

Molecular architecture of giant viruses infecting microbial eukaryotes (protists). [PDF]

BioTechnologia (Pozn)
Kyrychenko A.
europepmc   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source