Results 31 to 40 of about 27,996,561 (298)
Scientific Reports, 2021 The eukaryotic elongation factor-2 kinase, eEF2K, which restricts protein translation elongation, has been identified as a potential therapeutic target for diverse types of malignancies including triple negative breast cancer (TNBC).
YoungJun Ju +3 more
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Journal of Lipid Research, 2009 Glucosamine impairs hepatic apolipoprotein B100 (apoB100) production by inducing endoplasmic reticulum (ER) stress and enhancing cotranslational and posttranslational apoB100 degradation (Qiu, W., R. K. Avramoglu, A. C. Rutledge, J. Tsai, and K.
Wei Qiu +4 more
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Plants, 2021 The initiation stage of protein biosynthesis is a sophisticated process tightly regulated by numerous initiation factors and their associated components. However, the mechanism underlying translation initiation has not been completely understood in rice.
Yuqing Huang +4 more
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Journal of Biological Chemistry, 1979 [14C]Eukaryotic initiation factor 2 (eIF-2), obtained by reductive methylation of the purified initiation factor, was shown to be active in the unfractionated reticulocyte lysate. This allowed a direct measurement of the endogenous pool size of eIF-2 in rabbit reticulocyte lysate according to the principle of isotope dilution.
B, Safer, W, Kemper, R, Jagus
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Translation elongation can control translation initiation on eukaryotic mRNAs [PDF]
, 2013 Synonymous codons encode the same amino acid, but differ in other biophysical properties. The evolutionary selection of codons whose properties are optimal for a cell generates the phenomenon of codon bias.
Kazana, Eleanna +5 more
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EIF4A2 (eukaryotic translation initiation factor 4A, isoform 2) [PDF]
, 2000 Review on EIF4A2 (eukaryotic translation initiation factor 4A, isoform 2), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL
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Unanticipated antigens: translation initiation at CUG with leucine.
PLoS Biology, 2004 Major histocompatibility class I molecules display tens of thousands of peptides on the cell surface for immune surveillance by T cells. The peptide repertoire represents virtually all cellular translation products, and can thus reveal a foreign presence
Susan R Schwab +4 more
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F1000Research, 2015 Eukaryotic protein translation is divided into three mains stages: initiation, elongation and termination. Regulation of this process occurs at the initiation and elongation step.
Viviane Alves
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Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs
Life Science Alliance, 2020 This study highlights the role of transglutaminase 2 in selective mRNA translation of hypoxic cancer cells by polyamination-dependent modulation of 4EBPs, providing a target for cancer treatment.
Sung-Yup Cho +12 more
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Data in Brief, 2017 The data described in this article are related to “High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans” (Manfrini et ...
Nicola Manfrini +11 more
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