Results 51 to 60 of about 1,026 (162)
ChemistrySelect, Volume 10, Issue 21, June 4, 2025.In‐silico drug discovery pipeline for Mycetoma caused by Nocardia brasiliensis. A library of 1034 phytocompounds was screened to identify potent inhibitors, with Parviflorone F showing strong binding and stability against the 50S ribosomal unit. Molecular dynamics confirmed its inhibitory potential, offering a promising therapeutic candidate.
Sandra Jose +7 more
wiley +1 more source
Repurposing FDA-Approved Drugs for Eumycetoma Treatment: Homology Modeling and Computational Screening of CYP51 Inhibitors [PDF]
International Journal of Molecular SciencesMagdi Awadalla Mohamed +2 more
exaly +2 more sources
Coexistent actinomycosis and eumycetoma in an immunocompetent patient
Indian Journal of Dermatology, 2014 the patient may have taken, or due to the coloring agent titanium dioxide present in the tablet of levocetirizine. However, detailed history taking excluded possibility of both, as there was no other drug intake during last 4 weeks. Also, the patient did not develop any reaction on provocation with fexofenadine, which contained titanium dioxide.
Nagendra Singh Beniwal +5 more
openaire +3 more sources
Spinal Eumycetoma: A Rare Cause of Lumbar Canal Stenosis and Significance of “Dot in Circle”
Indian Journal of Radiology and Imaging, 2021 Mycetoma is a chronic granulomatous disease that is more common in tropical regions with predominant involvement of foot. Spinal mycetoma presenting as lumbar canal stenosis is extremely rare.
Radha Sarawagi +3 more
doaj +1 more source
Posaconazole treatment of refractory eumycetoma and chromoblastomycosis [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2005 Eumycetoma and chromoblastomycosis are chronic, disfiguring fungal infections of the subcutaneous tissue that rarely resolve spontaneously. Most patients do not achieve sustained long-term benefits from available treatments; therefore, new therapeutic options are needed.
Negroni, Ricardo +5 more
openaire +4 more sources
PLoS Neglected Tropical Diseases, 2020 BackgroundEumycetoma is a neglected tropical disease most commonly caused by the fungus Madurella mycetomatis. Identification of eumycetoma causative agents can only be reliably performed by molecular identification, most commonly by species-specific PCR.
Wilson Lim +8 more
doaj +1 more source
The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies
Chemical Biology &Drug Design, Volume 105, Issue 1, January 2025.The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley +1 more source
Two simultaneous mycetomas caused by Fusarium verticillioides and Madurella mycetomatis
Revista do Instituto de Medicina Tropical de São PauloMycetoma is a chronic granulomatous disease, classified into eumycetoma caused by fungi and actinomycetoma due to aerobic filamentous actinomycetes. Mycetoma can be found in geographic areas near the Tropic of Cancer.
Alexandro Bonifaz +4 more
doaj +1 more source
Phaeohyphomycosis caused by Trematosphaeria grisea in an immunocompromised English springer spaniel
Veterinary Record Case Reports, Volume 12, Issue 4, December 2024.Abstract A 10‐year‐old, male, farm‐based springer spaniel that presented with subacute progressive left‐sided central vestibular signs was diagnosed with meningoencephalitis of unknown origin. The patient received prednisolone (2 mg/kg/day orally), ciclosporin (5 mg/kg orally twice a day) and a single infusion of cytarabine (200 mg/m2). Six weeks later,
Erin Brennan +4 more
wiley +1 more source
Clinical Case Reports, Volume 12, Issue 6, June 2024.Key Clinical Message This case report explores the clinical journey of a patient initially diagnosed with botryomycosis, only to later reveal the underlying and rare condition of actinomycosis. The report highlights the challenges in getting to an accurate diagnosis, emphasizing the importance of considering uncommon pathologies, the utility of multi ...
Josiah Tatenda Masuka +5 more
wiley +1 more source