Results 61 to 70 of about 1,841 (191)

Role of Clinical Assessment, Identification of Bug, Antibiotics, and Surgery in Chronic Foot Infections: Case Series [PDF]

Journal of Foot and Ankle Surgery (Asia Pacific)
Introduction: Despite the increasing prevalence of foot infections, particularly in diabetic patients, limited evidence exists regarding their microbiological diversity and optimal treatment strategies for the management of chronic foot infections.
Vikas Madhav Agashe, Ayesha Sunavala, Aditya Menon, Madhav Chowdhry   +3 more
doaj   +1 more source

Canine eumycetoma caused by Madurella pseudomycetomatis

Medical Mycology Case Reports, 2022
Canine eumycetoma is a rare granulomatous disease caused by dematiaceous fungi. A 2-year-old Great Dane dog had a subcutaneous mass in the right thigh that was surgically removed. Grossly, numerous black-grains were visible. Histologically subcutaneous pyogranulomas were centered on myriads of pigmented fungal elements.
Francesco Albanese, Luisa Vera Muscatello, Alice Michelutti, Christian Falcaro, Laura Bellentani, Patrizia Danesi   +5 more
openaire   +3 more sources

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza, Michael Olubusayo Binuyo, Callixte Cyuzuzo, Acsa Igizeneza, Jean Paul Sinumvayo, Oluwaremilekun Grace Ajakaye, Egie Elisha Enabulele, Zororo Chinwadzimba, Ezera Agwu, Nicholas Midzi   +9 more
wiley   +1 more source

Development and efficacy of tryptophol-containing emulgel for reducing subcutaneous fungal nodules from Scedosporium apiospermum eumycetoma

Research in Pharmaceutical Sciences, 2022
Background and purpose: Subcutaneous infections caused by Scedosporium apiospermum present as chronic eumycetomatous manifestations in both immunocompromised and immunocompetent individuals.
Thitinan Kitisin, Watcharamat Muangkaew, Sumate Ampawong, Nichapa Sansurin, Natthawut Thitipramote, Passanesh Sukphopetch   +5 more
doaj   +1 more source

Plant‐Based Mycetoma Inhibitors Targeting the 50S Ribosomal Protein of Nocardia brasiliensis: In Silico Approach

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
In‐silico drug discovery pipeline for Mycetoma caused by Nocardia brasiliensis. A library of 1034 phytocompounds was screened to identify potent inhibitors, with Parviflorone F showing strong binding and stability against the 50S ribosomal unit. Molecular dynamics confirmed its inhibitory potential, offering a promising therapeutic candidate.
Sandra Jose, Manjunathan Jagadeesan, Meenambiga Setti Sudharsan, Pasiyappazham Ramasamy, Shyamala Gowri, Muthu Thiruvengadam, Sowmya Hari, Baskar Venkidasamy   +7 more
wiley   +1 more source

Kinome analysis of Madurella mycetomatis identified kinases in the cell wall integrity pathway as novel potential therapeutic drug targets in eumycetoma caused by Madurella mycetomatis

PLoS Neglected Tropical Diseases
Eumycetoma is a neglected tropical subcutaneous disease most commonly caused by the fungus Madurella mycetomatis. Currently, eumycetoma is treated by a combination of antifungal therapy and surgery, with limited success rates.
Mickey Konings, Nikolaos Strepis, Ri-ichiroh Manabe, Akira Hasegawa, Somdatta Y. Chaudhari, Saskia du Pré, Marij Schippers, M. Tagami, Jingyi Ma, Yasushi Okazaki, M. Todd, B. Biersack, V. Masand, Annelies Verbon, T. Kasukawa, I. Abugessaisa, Wendy W J van de Sande   +16 more
semanticscholar   +1 more source

Eumycetoma causative agents: A systematic review to inform the World Health Organization priority list of fungal pathogens

Medical Mycology
The World Health Organization, in response to the growing burden of fungal disease, established a process to develop a fungal priority pathogens list. This systematic review aimed to evaluate the epidemiology and impact of eumycetoma.
Julia E. Clark, H. Y. Kim, W. V. D. van de Sande, Brendan McMullan, P. Verweij, A. Alastruey‐Izquierdo, Arunaloke Chakrabarti, Thomas S Harrison, F. Bongomin, Roderick J Hay, R. Oladele, Jutta Heim, P. Beyer, Marcelo Galas, Siswanto Siswanto, D. Dagne, Felipe Roitberg, Valeria Gigante, J. Beardsley, Hatim Sati, Jan-Willem C. Alffenaar, C. O. Morrissey   +21 more
semanticscholar   +1 more source

Posaconazole treatment of refractory eumycetoma and chromoblastomycosis [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2005
Eumycetoma and chromoblastomycosis are chronic, disfiguring fungal infections of the subcutaneous tissue that rarely resolve spontaneously. Most patients do not achieve sustained long-term benefits from available treatments; therefore, new therapeutic options are needed.
Negroni, Ricardo, Tobón, Angela, Bustamante, Beatriz, Shikanai-Yasuda, Maria Aparecida, Patino, Hernando, Restrepo, Angela   +5 more
openaire   +4 more sources

The development of a novel diagnostic PCR for Madurella mycetomatis using a comparative genome approach.

PLoS Neglected Tropical Diseases, 2020
BackgroundEumycetoma is a neglected tropical disease most commonly caused by the fungus Madurella mycetomatis. Identification of eumycetoma causative agents can only be reliably performed by molecular identification, most commonly by species-specific PCR.
Wilson Lim, Emmanuel Siddig, Kimberly Eadie, Bertrand Nyuykonge, Sarah Ahmed, Ahmed Fahal, Annelies Verbon, Sandra Smit, Wendy Wj van de Sande   +8 more
doaj   +1 more source

Cranial mycetoma: A rare case report with review of literature

Journal of Global Infectious Diseases, 2021
Mycetoma is a chronic granulomatous infection caused by fungi or bacteria, known as eumycetoma and actinomycetoma, respectively. Mycetoma commonly affects young males belonging to low socioeconomic strata, usually barefooted agricultural workers.
Fouzia Siraj, Akanksha Malik, Sharma Shruti, K B Shankar, Swati Singh   +4 more
doaj   +1 more source