Results 71 to 80 of about 2,223 (217)

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

An approach to histology-based diagnosis and treatment of Madura foot

Journal of Infection in Developing Countries, 2012
Madura foot is a deep mycosis commonly seen in tropical and subtropical countries such as India. Its incidence is likely to rise in temperate regions as well, due to the increase in worldwide travel.
Sanjay Singh Chufal, Naveen Chandra Thapliyal, Manoj Kumar Gupta   +2 more
doaj   +1 more source

Transcriptome analysis of the two unrelated fungal β-lactam producers Acremonium chrysogenum and Penicillium chrysogenum: Velvet-regulated genes are major targets during conventional strain improvement programs [PDF]

, 2017
Background Cephalosporins and penicillins are the most frequently used β-lactam antibiotics for the treatment of human infections worldwide. The main industrial producers of these antibiotics are Acremonium chrysogenum and Penicillium chrysogenum, two ...
Dominik Terfehr, Tim A. Dahlmann, Ulrich Kück   +2 more
core   +1 more source

Posaconazole treatment of refractory eumycetoma and chromoblastomycosis [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2005
Eumycetoma and chromoblastomycosis are chronic, disfiguring fungal infections of the subcutaneous tissue that rarely resolve spontaneously. Most patients do not achieve sustained long-term benefits from available treatments; therefore, new therapeutic options are needed.
Negroni, Ricardo, Tobón, Angela, Bustamante, Beatriz, Shikanai-Yasuda, Maria Aparecida, Patino, Hernando, Restrepo, Angela   +5 more
openaire   +4 more sources

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza, Michael Olubusayo Binuyo, Callixte Cyuzuzo, Acsa Igizeneza, Jean Paul Sinumvayo, Oluwaremilekun Grace Ajakaye, Egie Elisha Enabulele, Zororo Chinwadzimba, Ezera Agwu, Nicholas Midzi   +9 more
wiley   +1 more source

MRI findings in cranial eumycetoma

Indian Journal of Radiology and Imaging, 2011
AbstractCranial eumycetoma (CE) due to direct inoculation of Madurella grisea into the scalp is extremely rare. We describe a case of CE caused by direct inoculation of M. grisea with the characteristic MRI findings of the "dot-in-circle" sign and a conglomeration of multiple, extremely hypointense "dots."
Munawwar Ahmed, Jyoti Sureka, Geeta Chacko, Anu Eapen   +3 more
openaire   +3 more sources

Plant‐Based Mycetoma Inhibitors Targeting the 50S Ribosomal Protein of Nocardia brasiliensis: In Silico Approach

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
In‐silico drug discovery pipeline for Mycetoma caused by Nocardia brasiliensis. A library of 1034 phytocompounds was screened to identify potent inhibitors, with Parviflorone F showing strong binding and stability against the 50S ribosomal unit. Molecular dynamics confirmed its inhibitory potential, offering a promising therapeutic candidate.
Sandra Jose, Manjunathan Jagadeesan, Meenambiga Setti Sudharsan, Pasiyappazham Ramasamy, Shyamala Gowri, Muthu Thiruvengadam, Sowmya Hari, Baskar Venkidasamy   +7 more
wiley   +1 more source

Role of Clinical Assessment, Identification of Bug, Antibiotics, and Surgery in Chronic Foot Infections: Case Series [PDF]

Journal of Foot and Ankle Surgery (Asia Pacific)
Introduction: Despite the increasing prevalence of foot infections, particularly in diabetic patients, limited evidence exists regarding their microbiological diversity and optimal treatment strategies for the management of chronic foot infections.
Vikas Madhav Agashe, Ayesha Sunavala, Aditya Menon, Madhav Chowdhry   +3 more
doaj   +1 more source

Development and efficacy of tryptophol-containing emulgel for reducing subcutaneous fungal nodules from Scedosporium apiospermum eumycetoma

Research in Pharmaceutical Sciences, 2022
Background and purpose: Subcutaneous infections caused by Scedosporium apiospermum present as chronic eumycetomatous manifestations in both immunocompromised and immunocompetent individuals.
Thitinan Kitisin, Watcharamat Muangkaew, Sumate Ampawong, Nichapa Sansurin, Natthawut Thitipramote, Passanesh Sukphopetch   +5 more
doaj   +1 more source

An updated list of eumycetoma causative agents and their differences in grain formation and treatment response. [PDF]

Clin Microbiol Rev
van de Sande WWJ, Fahal AH.
europepmc   +3 more sources