Results 101 to 110 of about 6,679,772 (342)

A Real-World Energy Management Dataset from a Smart Company Building for Optimization and Machine Learning

Scientific Data
We present a large real-world dataset obtained from monitoring a smart company facility over the course of six years, from 2018 to 2023. The dataset includes energy consumption data from various facility areas and components, energy production data from ...
Jens Engel, Andrea Castellani, Patricia Wollstadt, Felix Lanfermann, Thomas Schmitt, Sebastian Schmitt, Lydia Fischer, Steffen Limmer, David Luttropp, Florian Jomrich, René Unger, Tobias Rodemann   +11 more
doaj   +1 more source

When Does Sexuality-Based Discrimination Motivate Political Participation?

, 2017
The established consensus in political behavior research is that discrimination by political institutions motivates marginalized groups to vote and protest their conditions.
Page, Douglas D.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Coopératives, Europe : Cooperatives Europe [PDF]

Revue internationale de l'économie sociale: Recma, 2006
Cooperatives Europe a ete creee le 1er mars 2005 pour conjuguer les forces cooperatives au niveau europeen, initiant un processus d’integration qui se poursuit en 2006. Gagner en visibilite pour faire entendre les specificites cooperatives aupres des institutions europeennes est un objectif important.
openaire   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Clinical challenges and patient experiences in early-onset colorectal cancer: insights from seven European countries

BMC Gastroenterology
Background The incidence of early-onset colorectal cancer (eoCRC), defined as CRC diagnosed in individuals under 50, is rising globally. Younger patients often face diagnostic delays and receive care pathways designed for older populations.
Marianna Vitaloni, Katell Maguet, Andi Carlan, Patricia Stack, Vincent de Jong, Ross Williams, Zorana Maravic   +6 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The Healthcare Professionals’ and Patient Advocates’ Perspectives on the Care for Children with Cancer in Europe—A Report from the ESCALIER Project

Current Oncology
Cancer in children and adolescents is rare. Therefore, experienced multidisciplinary teams of health care professionals and input from patient advocates are needed.
Maria Otth, Marko Ocokoljic, Theodora Armenkova, Irina Ban, Samira Essiaf, Maximilian Hopfgartner, Lejla Kameric, Pamela R. Kearns, Georgia Kokkinou, Carmelo Rizzari, Carina Schneider, Katrin Scheinemann   +11 more
doaj   +1 more source

The Trade and Development Policy of the European Union [PDF]

, 2007
Lorand Bartels
openalex   +1 more source

Returnees in the Maghreb. A European perspective. Egmont Security Policy Brief No. 120 December 2019 [PDF]

, 2019
More than 10,000 individuals travelled from Europe and North Africa to fight in Syria and Iraq. Now, Europe and North Africa are dealing with the challenge of returning foreign fighters, mostly separately.
Renard, Thomas
core