Results 51 to 60 of about 6,679,772 (342)

The DART-Europe project: towards developing a European theses portal [PDF]

open access: yes, 2005
This paper will report on the new European theses project DART-Europe. The purpose of this project is to align institutional and national e-theses developments across Europe with the wider open archives movement by the construction of a European portal ...
Ayris, P.   +3 more
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The impact of the National Institute for Health Research Health Technology Assessment programme, 2003–13: a multimethod evaluation

open access: yesHealth Technology Assessment, 2015
Background: The National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme supports research tailored to the needs of NHS decision-makers, patients and clinicians. This study reviewed the impact of the programme, from 2003
Susan Guthrie   +5 more
doaj   +1 more source

Deaths Exceed Births in Most of Europe, But Not in the United States [PDF]

open access: yes, 2015
In this brief, authors Kenneth Johnson, Layton Fields, and Dudley Poston, Jr. present important new findings about the diminishing number of births compared to deaths in Europe and the United States from their recent article in Population and Development
Fields, Layton M.   +2 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Water in Europe [PDF]

open access: yes, 2008
An overview of trends in the water sector in Europe and the companies ...
Hall, David, Lobina, Emanuele
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Foundation models for materials discovery – current state and future directions

open access: yesnpj Computational Materials
Large language models, commonly known as LLMs, are showing promise in tacking some of the most complex tasks in AI. In this perspective, we review the wider field of foundation models—of which LLMs are a component—and their application to the field of ...
Edward O. Pyzer-Knapp   +7 more
doaj   +1 more source

Learning for the NHS on procurement and supply chain management: a rapid evidence assessment

open access: yesHealth Services and Delivery Research, 2014
Background: Procurement of clinical and non-clinical goods has been identified as one area for efficiency savings for the NHS. There is a need for robust evidence to help the NHS make informed decisions about how to make such savings and there is ...
Saba Hinrichs   +4 more
doaj   +1 more source

Whither growth in central and eastern Europe? Policy lessons for an integrated Europe [PDF]

open access: yes
In this Blueprint, Bruegel Resident Fellows Zsolt Darvas, Jean Pisani-Ferry, André Sapir and their co-authors Torbjörn Becker, Daniel Daianu, Vladimir Gligorov, Michael A Landesmann, Pavle Petrovic, Dariusz K.
André Sapir   +8 more
core   +1 more source

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