Results 51 to 60 of about 2,046,421 (291)
History of the Human Sciences, 2018 Psychotherapy was an invention of European modernity, but as the 20th century unfolded, and we trace how it crossed national and continental borders, its goals and the particular techniques by which it operated become harder to pin down. This introduction briefly draws together the historical literature on psychotherapy in Europe, asking comparative ...
openaire +3 more sources
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Growing strings in a chemical reaction space for searching retrosynthesis pathways
npj Computational MaterialsMachine learning algorithms have shown great accuracy in predicting chemical reaction outcomes and retrosyntheses. However, designing synthesis pathways remains challenging for existing machine learning models which are trained for single-step prediction.
Federico Zipoli +4 more
doaj +1 more source
Urban Pluvial Flood Risk in Romania, in the Context of Floods Directive Implementation [PDF]
Aerul şi Apa: Componente ale MediuluiRomania is a flood prone country and same are her cities. Pluvial floods can occur in urban or rural areas without a direct connection with river or a water body. As part of the Floods Directive implementation, Romania has identified, in the first cycle,
T. SAMPSON +3 more
doaj +1 more source
Population & Avenir, 2009 It is often said that Europe is the most ill-defined of continents. As a result, the size of the European population and its relative weight in the world vary according to the geographic area selected. Seven such areas can be identified.
openaire +2 more sources
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
The inherent adversarial robustness of analog in-memory computing
Nature CommunicationsA key challenge for deep neural network algorithms is their vulnerability to adversarial attacks. Inherently non-deterministic compute substrates, such as those based on analog in-memory computing, have been speculated to provide significant adversarial ...
Corey Lammie +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source