Results 81 to 90 of about 2,046,421 (291)

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Politeness in Europe

open access: yesStudies in Applied Linguistics & TESOL, 2005
Is this true of all Westerners? And what exactly do we mean by Westerner? If a similar exchange were to take place, say, in an elevator in Helsinki, could we draw the same conclusions? Indeed, would such an exchange take place in Helsinki at all? In Nicosia? In Tallinn? Leo Hickey and Miranda Stewart’s delightful new volume, Politeness in Europe, takes
openaire   +4 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Spin-photon entanglement with direct photon emission in the telecom C-band

open access: yesNature Communications
Quantum networks, relying on the distribution of quantum entanglement between remote locations, have the potential to transform quantum computation and secure long-distance quantum communication.
P. Laccotripes   +5 more
doaj   +1 more source

The Asylums of Europe [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1880
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openaire   +2 more sources

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