Results 81 to 90 of about 5,879,476 (365)
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Communications MaterialsHole spins in Ge/SiGe heterostructures have emerged as an interesting qubit platform with favourable properties such as fast electrical control and noise-resilient operation at sweet spots.
Leonardo Massai +10 more
doaj +1 more source
Urban Pluvial Flood Risk in Romania, in the Context of Floods Directive Implementation [PDF]
Aerul şi Apa: Componente ale MediuluiRomania is a flood prone country and same are her cities. Pluvial floods can occur in urban or rural areas without a direct connection with river or a water body. As part of the Floods Directive implementation, Romania has identified, in the first cycle,
T. SAMPSON +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
History of the Human Sciences, 2018 Psychotherapy was an invention of European modernity, but as the 20th century unfolded, and we trace how it crossed national and continental borders, its goals and the particular techniques by which it operated become harder to pin down. This introduction briefly draws together the historical literature on psychotherapy in Europe, asking comparative ...
openaire +3 more sources
Growing strings in a chemical reaction space for searching retrosynthesis pathways
npj Computational MaterialsMachine learning algorithms have shown great accuracy in predicting chemical reaction outcomes and retrosyntheses. However, designing synthesis pathways remains challenging for existing machine learning models which are trained for single-step prediction.
Federico Zipoli +4 more
doaj +1 more source
How IGN (France) computed the so-called 'centre of gravity' of physical Europe in 1989 and 2004 [PDF]
arXiv, 2019 The method used by senior geodetic engineer Jean-Georges Affholder to determine what can be termed as the 'centre of gravity' of physical Europe in 1989 and 2004 relies on mathematical formulae which, in their only published version, happen to be flawed with typographical errors that do not reflect Mr. Affholder's actual mathematical exactness.
arxiv
The need for ‘Diamond Engagement’ around open access to high quality research output [PDF]
This paper advocates for a co-ordinated cultural shift in their engagement with access to resources in order to make peer-reviewed articles available to a wider audience.
Science Europe
core
The historical regions of Europe: civilizational backgrounds and multiple routes to modernity [PDF]
, 2012 A systematic typology or comparative analysis of European historical regions does not exist and there is relatively little literature on the topic. The argument in this paper is that a six-fold classification is needed to capture the diversity of Europe ...
Delanty, Gerard
core +2 more sources