Results 51 to 60 of about 202,649 (296)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

An epidemiological knowledge graph extracted from the World Health Organization’s Disease Outbreak News

open access: yesScientific Data
The rapid evolution of artificial intelligence (AI), together with the increased availability of social media and news for epidemiological surveillance, is marking a pivotal moment in epidemiology and public health research.
Sergio Consoli   +9 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The overlooked impacts of freshwater scarcity on oceans as evidenced by the Mediterranean Sea

open access: yesNature Communications
Water stress is an urgent issue in many regions worldwide, particularly in southern European countries. This study reveals the consequences of decreased freshwater flow on marine ecosystems in the Mediterranean Sea due to climate change and escalating ...
Diego Macias   +16 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Estimation of shipping emissions using vessel Long Range Identification and Tracking data

open access: yesJournal of Maps, 2017
Shipping is a growing source of air pollutants and greenhouse gases, which are emitted mainly over an international territory, the seas, for which only shared responsibility by all countries is felt.
Alfredo Alessandrini   +5 more
doaj   +1 more source

Sustainable development in developing countries: The African, Caribbean and pacific observatory /Darnus vystymasis besivystančiose šalyse: Afrikos, Karibų ir ramiojo vandenyno valstybių apžvalga

open access: yesTechnological and Economic Development of Economy, 2010
Freshwater, aquaculture, fisheries, biodiversity, forests, and agricultural land have high economic and social value throughout the Africa, Caribbean and Pacific (ACP) region; but they can also be over‐exploited, with damaging consequences for local ...
Paolo Roggeri   +7 more
doaj   +1 more source

European Commission support [PDF]

open access: yesGerontechnology, 2001
The Directorates of the European Commission have a history of 20 years in programming research and technology development in so-called framework programs. Age-related programs addressed Technological Issues of relevance to the ageing population of Europe.
openaire   +1 more source

The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality [PDF]

open access: hybrid, 2021
Tom H Karlsen   +56 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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