Results 61 to 70 of about 202,756 (248)

OER: A European policy perspective

Journal of Interactive Media in Education, 2014
The potential benefits of OER have led many European governments to implement policies supporting their creation and use. This article aims to put these OER policies in context, discussing their focus and scope and highlighting challenges and bottlenecks.
Jesús Maria Alquézar Sabadie, Jonatan Castaño Muñoz, Yves Punie, Christine Redecker, Riina Vuorikari   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

GCoM datasets: a collection of climate and energy action plans with mitigation, adaptation and energy access commitments

Scientific Data
This paper presents a collection of datasets holding information on the energy and climate action plans of 6,850 municipalities, taking part in the transnational initiative of the Global Covenant of Mayors (GCoM). This collection includes commitments for
Camilo Franco, Giulia Melica, Aldo Treville, Marta Giulia Baldi, Valentina Palermo, Paolo Bertoldi, Enrico Pisoni, Fabio Monforti-Ferrario, Monica Crippa   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Mapping the potential of Natural Pest Control services in pan-European landscapes at 50 m resolution

Scientific Data
Natural pest control is a crucial regulating ecosystem service for sustaining crop yields while lowering pesticide use. Its effectiveness depends on landscape complexity, particularly the amount and spatial arrangement of semi-natural habitats, in and ...
Rui Catarino, Ana Klinnert, Ana Luisa Barbosa, Raphael d’Andrimont, Thomas Fellmann, Renate Koeble, Maria Luisa Paracchini, Jean-Michel Terres, Marijn van der Velde, Peter Vogt, Carlo Rega   +10 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Towards sustainable food systems: developing a monitoring framework for the EU

Frontiers in Sustainable Food Systems
Adequate monitoring of the EU transition toward sustainable food systems can promote policy coherence and provide better evidence for informed policy making.
Szvetlana Acs, João Costa Leite, Esther Sanyé-Mengual, Arnaldo Caivano, Rui Catarino, Jean-Noël Druon, Federica Di Marcantonio, Beyhan De Jong, Irene Guerrero, Patricia Gurría, Robert M’barek, Panos Panagos, Carolina Puerta-Piñero, Saulius Tamosiunas, Jan Wollgast, Katalin Tóth   +15 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

European Commission Revealed? The European Commission and the Enlargement [PDF]

, 2021
openaire   +1 more source