Results 51 to 60 of about 202,756 (248)

An epidemiological knowledge graph extracted from the World Health Organization’s Disease Outbreak News

open access: yesScientific Data
The rapid evolution of artificial intelligence (AI), together with the increased availability of social media and news for epidemiological surveillance, is marking a pivotal moment in epidemiology and public health research.
Sergio Consoli   +9 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The overlooked impacts of freshwater scarcity on oceans as evidenced by the Mediterranean Sea

open access: yesNature Communications
Water stress is an urgent issue in many regions worldwide, particularly in southern European countries. This study reveals the consequences of decreased freshwater flow on marine ecosystems in the Mediterranean Sea due to climate change and escalating ...
Diego Macias   +16 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Sustainable development in developing countries: The African, Caribbean and pacific observatory /Darnus vystymasis besivystančiose šalyse: Afrikos, Karibų ir ramiojo vandenyno valstybių apžvalga

open access: yesTechnological and Economic Development of Economy, 2010
Freshwater, aquaculture, fisheries, biodiversity, forests, and agricultural land have high economic and social value throughout the Africa, Caribbean and Pacific (ACP) region; but they can also be over‐exploited, with damaging consequences for local ...
Paolo Roggeri   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Estimation of shipping emissions using vessel Long Range Identification and Tracking data

open access: yesJournal of Maps, 2017
Shipping is a growing source of air pollutants and greenhouse gases, which are emitted mainly over an international territory, the seas, for which only shared responsibility by all countries is felt.
Alfredo Alessandrini   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

High resolution assessment of air quality and health in Europe under different climate mitigation scenarios

open access: yesNature Communications
Climate change mitigation policies lower greenhouse gas emissions and generally reduce fine particulate matter (P M 2.5) concentrations, hereby bringing health co-benefits.
Enrico Pisoni   +10 more
doaj   +1 more source

Prompt fission neutron emission: Problems and challenges

open access: yesEPJ Web of Conferences, 2013
This paper presents some of the challenges ahead of us even after 75 years of the discovery of the fission process and large progress made since then. The focus is on application orientation, which requires improved measurements on fission cross-sections
Hambsch F.-J.   +7 more
doaj   +1 more source

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