Results 91 to 100 of about 849,945 (312)

Privacy, Expression and the World Wide Web. Shall we Forget? [PDF]

open access: yes, 2014
Google v Spain is an important judgment of the Court of Justice of the European Union which has important implications for the rights of individuals’ privacy, the Court’s use of a purposive method of interpretation, the regulation of search engines ...
Ferris, Katy
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

(Conflict) principles of European (consumer) contract law : an update [PDF]

open access: yes, 2004
In April 2003 I commented on the European Commission’s Action Plan on a More Coherent European Contract Law [COM(2003) 68 final] and the Green Paper on the Modernisation of the 1980 Rome Convention [COM(2002) 654 final].1 While the main argument of that ...
Calliess, Gralf-Peter
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Improving EU Constitutional Politics? A Preliminary Assessment of the Convention [PDF]

open access: yes
The Convention appears to many as both a confirmation of the thesis of the new institutionalism on the value of institutions for shaping the outcome of constitutional politics (the politics of creating EU fundamental rules) and a new model for democratic
Carlos Closa
core  

Liberty versus security? EU asylum policy and the European Commission [PDF]

open access: yes, 2009
The Common European Asylum System (CEAS) experienced significant developments during the Tampere programme (1999 – 2004). This article analyses how security is constituted or viewed by the European Union in the area of asylum policy; more importantly how
Kaunert, C
core   +2 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

The Effects of the European Convention on Human Rights and the Strasbourg Case Law on the Development of Hungarian Law [PDF]

open access: yes, 2015
The European Convention on Human Rights is a milestone in the development of international law, aimed at guarding fundamental freedoms and human rights in Europe.
Szabó, Marcel
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Difference as a Potential for European Constitution-Making [PDF]

open access: yes
In the following contribution I propose an analytical approach in which dealing with differences in decision-making is the central factor in explaining the output of European governance. It is the hypothesis that differences can, under certain conditions,
Christine Landfried
core  

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