Results 101 to 110 of about 849,945 (312)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

KEDUDUKAN HUKUM CYBER CRIME DALAM PERKEMBANGAN HUKUM INTERNASIONAL KONTEMPORER

open access: yesMasalah-Masalah Hukum, 2013
Cybercrime is anewrange ofinternational law, particularlyinternationalcriminallaw. The existence ofcybercrimeis now afactthatshouldbe taken seriouslybythe international community.lmmediateresponseformto do is to regulate the cybercrime ...
Maskun Maskun   +3 more
doaj   +1 more source

The Importance of Being Nice: An Institutionalist Analysis of French Preferences on the Future of Europe [PDF]

open access: yes
This article offers an institutionalist explanation of French preferences on the future of Europe from the Maastricht Treaty of 1992 through the Constitutional Treaty of 2004. It argues that the autonomous institutional logic of the constitution-drafting
Nicolas Jabko
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The European Convention on Human Rights

open access: yesEIRP Proceedings, 2015
Since 1950 - when it was ratified – the European Convention on Human Rights has had a decisive impact on the legislation, jurisprudence and judicial practice of the signatory States of its text.
Cătălina Mititelu
doaj  

The (Un)Likely Emergence of a “Right to Die” under the European Convention on Human Rights

open access: yesReview of European and Comparative Law
This article discusses the question of whether the right to die is likely to emerge under the European Convention on Human Rights. In recent decades, several member states of the Council of Europe have changed their legal frameworks by decriminalizing ...
Camelia-Claudia Muresan
doaj   +1 more source

PARALLEL BETWEEN THE REFUGEE CONCEPT ACCORDING TO THE CONVENTION RELATING TO THE STATUS OF REFUGEES FROM 1951 AND ITS PROTOCOL FROM 1967 AND THE REFUGEE CONCEPT ACCORDING TO EUROPEAN LAW [PDF]

open access: yesChallenges of the Knowledge Society, 2018
In this study our aim is to make a comparison between the refugee concept according to the Convention Relating to the Status of Refugees from 1951 and its Protocol from 1967 which represent the international approach and the refugee concept according ...
Patricia Casandra PAPUC
doaj  

Европейская ландшафтная конвенция в контексте зеленой экономики [PDF]

open access: yes, 2016
The European convention on landscapes (European Landscape Convention) has been adopted at the 718th meeting of Committee of Ministers of the Council of Europe (Strasbourg, on July 19, 2000), nominated to signing on October 20, 2000 at Conference of ...
Лебедева, Н. О.   +1 more
core  

European Court of Human Rights : Pendov v. Bulgaria [PDF]

open access: yes, 2020
The European Court of Human Rights (ECtHR) has delivered a judgment in which if found, apart from a violation of Article 1 of the First Protocol to the European Convention on Human Rights (ECHR), a breach of the applicant’s right to freedom of expression
Voorhoof, Dirk
core   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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