Results 41 to 50 of about 9,910 (255)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Московский журнал международного права, 2008 Russia’s accession to European standards of human rights and freedom is a very complicated process and the mechanism of implementation of the European Convention on the protection of human rights and fundamental freedoms is far from ideal.
A. M. Nikolaev
doaj +1 more source
Interim Measure and its enforcement in the European Court of Human Rights case-law [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2019 The European Court of Human Rights whose main mission is to consider individual and States petitions in case of the violation of the European Convention on Human Rights and Fundamental Freedoms and its additional protocols, based on the applicant’s ...
Mehryar Dashab
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Baltic Journal of Law & Politics, 2016 The European Convention on Human Rights does not provide for a prisoner’s right to parole and no international or regional human rights instrument provides for this right. However, recently, in the case of Öcalan v Turkey (No.
Mujuzi Jamil Ddamulira
doaj +1 more source
Evolution interpretation and the European consensus before the European court of human rights
Espaço Jurídico, 2019 The interpretation of the European convention on human rights has been shaped by rich jurisprudence of the European Court of human rights which on several occasions had to resort to so-called evolutive interpretation based on the concept of European ...
Pavel Bureš
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The Death of Democracy and the Forces of Power and Control: The Case of Europe
Social Sciences, 2016 At the time of writing, the United Kingdom is grabbling with its decision to abandon its European Union membership. As the country is divided and hate incidents are increased by almost 50%, this think-piece presents a critical analysis of Europe’s missed
Theo Gavrielides
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source