Results 31 to 40 of about 69,467 (236)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
PROPOSED UNIFIED PATENT LITIGATION SYSTEM IN EU
The paper deals with the proposed Unified Patent Litigation System in EU. After introductory notes on the reasons for proposing this system, the first part of the article is dedicated to the European Patent Court.
Jelena Ćeranić
doaj
A Longitudinal dataset of sector-level patent data for EuropeMendeley Data
This paper presents a comprehensive dataset of patent applications and grants at the 2-digit ISIC Rev.4/NACE Rev.2 sector level for a set of 24 European countries from 1985 to 2020.
P. Dimas, D. Stamopoulos, A. Protogerou
doaj +1 more source
Comity in International Intellectual Property Law: Analyzing the Jurisprudence of the Unified Patent Court Regarding Its Concurrent Jurisdiction with the European Patent Office [PDF]
Comity has long been considered and invoked by international courts and tribunals for various purposes. Particularly, some courts and tribunals have referred to comity when addressing problems such as potential conflicting decisions.
Jinyup Kim
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The paper deals with the Unified Patent Court established for the settlement of disputes relating to European patents and European patents with unitary effect.
Jelena Ćeranić
doaj
Aktywność patentowa w sektorze rolno-spożywczym a inteligentne specjalizacje województw Polski
The article concerns patent activity in the agri-food sector in the regions of Poland and its comparison with smart specialisations of Polish regions, defined in the process of implementing the European Structural and Investment Funds, 2014–2020.
Krzysztof Klincewicz
doaj +1 more source

