Results 41 to 50 of about 409,783 (282)

Patent Enforcement: A Comparative Review Preventing Patent Trolling in Europe

open access: yesThe Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2018
The US has made significant progress in the patent legislation landscape as evidenced by the US Patent Act in the Constitution and America Invents Act (AIA) of 2011.
Benjamin FRANCO, Cristian BANACU
doaj   +1 more source

Patent portfolios and pharmaceuticals: a european perspective

open access: yesMarket and Competition Law Review, 2023
The book deals with a complex subject, although far from new, which is the intersection between intellectual property (IP) and competition law. Indeed, exclusive rights confer market power and restrict competition temporarily.
Sílvia Bessa Venda
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Technological Monitoring Study Based on Invention Patents of Omeprazoleand Derivatives with Pharmaceutical Applications

open access: yesJournal of Technology Management & Innovation, 2010
The current study intends to present the relevance of omeprazole, esomeprazole, rabeprazole, pantoprazole and lansoprazole by means of the technological foresight study, through invention patent documents from Brazilian applicants as indicators of ...
Leandra Guimarães de Oliveira   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

esp@cenet@ Europe's Network of Patent Databases.

open access: yesIssues in Science and Technology Librarianship, 2006
The article presents information on the esp@cenet database developed by the European Patent Office in October 1998. The database features patent documents from Europe, Japan, the U.S. and the World Intellectual Property Organization. The coverage of the
Michael J. White
doaj   +1 more source

Patenting insurance related business methods: predictability and risk [PDF]

open access: yes, 2003
This paper raises and responds to questions concerning the patentability of business method patents. It explores the utility of patent applications in informing business method innovators of the risks associated with using the patent system.
Soetendorp, Ruth
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Make-or-Buy Decisions in Patent Related Services [PDF]

open access: yes, 2006
Among the most prominent theoretical frameworks dealing with the economic underlyings of firms’ make-or-buy decisions are Transaction Cost Economics (TCE) and the Resourced Based View (RBV).
Wagner, Stefan
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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