Results 151 to 160 of about 19,199 (198)

An atlas of genetic effects on the monocyte methylome across European and African populations. [PDF]

Genome Med
Zhang W, Qiu C, Zhang X, Zhang Z, Su KJ, Luo Z, Liu M, Zhao B, Wu L, Tian Q, Shen H, Wu C, Deng HW.   +12 more
europepmc   +1 more source

Omics Biomarkers in Precision Oncology: From the Lens of the ASCPT Biomarkers and Translational Tools and Oncology Communities

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Omics biomarkers comprise several molecular entities, including genomic, epigenomic, transcriptomic, proteomic, and metabolomic signatures. They play an essential role in oncology drug development and clinical settings by enabling personalized medicine.
Mai Mehanna, Hardik Mody, Joy C. Hsu, Julia Quintanilha, Zachary L. Taylor, Angela James, Binita Rajbanshi, Pooja Manchandani, Lakshmi Manasa Chekka   +8 more
wiley   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, Volume 293, Issue 15, Page 4554-4577, August 2026.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Ancestry Matters in Decoding Immunity

Immunology &Cell Biology, Volume 104, Issue 7, Page 708-710, August 2026.
The Chinese Immune Multi‐Omics Atlas (CIMA) establishes a population‐scale immune multi‐omics atlas by profiling over 10 million peripheral blood mononuclear cells from 428 Chinese adults using paired scRNA‐seq and scATAC‐seq. This resource mitigates longstanding European ancestry bias in single‐cell genomics and enables cell type resolved regulatory ...
Kesong Wu, Amanda J. Oliver, Zewen Kelvin Tuong   +2 more
wiley   +1 more source

Moving from a taxonomic to a functional perspective in global microbiome analysis requires optimizing multiplexing ratios. [PDF]

mSystems
Zielińska K, Pantiukh K, Org E, Łabaj PP, Kosciolek T.   +4 more
europepmc   +1 more source

Orchid genome evolution and trait innovation

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2577-2607, August 2026.
Orchids became one of the world's most diverse plant groups through genome‐driven innovations, unique relationships with fungi and pollinators, and remarkable adaptability. This review explains the origins of orchids and the evolution of their distinctive life forms, flowers, and ecological strategies and highlights promising directions for future ...
Meng‐Yao Zeng, Cheng‐Yuan Zhou, Linying Wang, Jie Gao, Weilun Yin, Dong‐Hui Peng, Siren Lan, Feng‐Xi Yang, Zhong‐Jian Liu   +8 more
wiley   +1 more source

A population-scale multi-omics blueprint of immune gene regulation. [PDF]

Clin Transl Med
Ventura AB, Deligio L, Volpe G.
europepmc   +1 more source

NUP153 immunoreactivity in neuroendocrine neoplasms supports the diagnosis of NET versus NEC and is modulated by post‐translational modifications

Journal of Neuroendocrinology, Volume 38, Issue 8, August 2026.
Abstract Nucleoporins (NUPs) constitute the nuclear pore complex (NPC) and are essentially involved in nuclear transport, chromatin organization, and context‐dependent gene regulation. However, the role of NUPs in neuroendocrine (tumor)biology and related diagnostic potential is poorly defined.
Sven Mattern, Arslan Ali, Vanessa Hollfoth, Eyyub Bag, Katharina Kluthe, Esther Herpel, Frank Bergmann, Thomas Muley, Michael Meister, Judith Lehmann‐Koch, Benjamin Goeppert, Arne Warth, Kai Breuhahn, Irina Bonzheim, Stephan Singer, Kerstin Singer   +15 more
wiley   +1 more source

Integrated Transcriptomic Analysis Identifies a Six-Gene Prognostic Signature, RNA Editing Derived Neoantigens, and miRNA Regulatory Networks in Renal Cell Carcinoma. [PDF]

Iran J Med Sci
Mehmandoostli Z, Dehghani Ashkezari M, Seifati SM, Kardar GA.   +3 more
europepmc   +1 more source

Dissecting the shared genetic architecture of bipolar disorder, major depressive disorder, and attention-deficit hyperactivity disorder. [PDF]

PLoS One
Lawrence C, Hansen TF.
europepmc   +1 more source