Results 121 to 130 of about 9,251,887 (309)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

The European Council [Dublin Summit 1990], Dublin, 28 April 1990 [PDF]

open access: yes, 1989
Dossier: Summary and conclusions, press conference European Commission President Jacques Delors, statement of European Council President Charles ...

core  

Evolution of Food Trade Networks from a Comparative Perspective: An Examination of China, the United States, Russia, the European Union, and African Countries

open access: yesFoods
In the intricate landscape of the global food system, a nuanced understanding of dynamic evolution patterns and driving mechanisms of food trade network is essential for advancing insights into the African food trade and maintaining the food security of ...
Wei Hu   +6 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

How is disinformation addressed in the member states of the European Union? : 27 country cases [PDF]

open access: yes
Published online: 18 June 2025Contributing authors: Konrad Bleyer-Simon, Minna Aslama Horowitz, Madalina Botan, Mato Brautovic, Elda Brogi, Ianis Bucholtz, Eileen Culloty, Beata Gavurova, Anja Grabovac, Socrates Ioakem, Jan Erik Kermer, Keith Kiely ...

core   +1 more source

DEVELOPMENT OF THE EUROPEAN UNION’S POLICY TOWARDS FAILED STATES IN THE 1990S

open access: yesВестник Кемеровского государственного университета, 2015
The notion of ―failed state‖ was introduced by the scientific society as long ago as in 1993, but it appeared in the official documents of the European Union only ten years after, in the European Security Strategy.
M. S. Miroshnikov
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

(Re)theorising European Integration under Globalisation:A Political Economy Approach [PDF]

open access: yes, 2004
In the last two decades, the European Union has become wider and deeper. In addition, the number of regional integration arrangements has increased dramatically since early 1990s. Against these developments, the focus of regional and European integration
Ugur, Mehmet.
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Redesigning the Spanish and Portuguese Welfare States: The Impact of Accession into the European Union. CES Working Paper, no. 85, 2001 [PDF]

open access: yes, 2001
Despite the fact that the norms issued by the European Union regarding the regulation of social protection policies are scant, becoming a member of such a supranational institution can be expected to have influenced the redesign of welfare states.
Alvarez, Santiago,   +2 more
core  

Home - About - Disclaimer - Privacy