Results 51 to 60 of about 354,025 (268)

Epilogue. High Hopes:Autonomy and the Identity of the EU

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2023 8(3), 1495-1511 | Article | (Table of Contents) I. Introduction. – II. The identity of the EU and European values. – III. A constitutional moment: becoming a member of the EU. –
Koen Lenaerts, José A. Gutiérrez-Fons
doaj   +1 more source

Electrochemical Characterization of Various Synthesized Quantum Dots and the Effect of Aging and Storage Way

International Journal of Electrochemical Science, 2015
New type of quantum dots (QDs) are synthesized using various types of passivators, thus the question of their stability and way of storage is still opened not only due to characterization but also due to their wide application (chemistry, chemical ...
David Hynek, Katerina Tmejova, Vedran Milosavljevic, Amitava Moulick, Pavel Kopel, Vojtech Adam, Rene Kizek   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

European Union Funds – Application Perspective

Studia Europejskie
The result of an effective management of the redistribution of European Union funds should be a reduction of disparities between EU regions by guaranteeing their comprehensive and harmonious development and supporting the economic and social cohesion of ...
Przemysław Dubel, Julita Majczyk
doaj   +1 more source

Sosedka Pegmatite Metal Ions Composition Determined by Voltammetry

International Journal of Electrochemical Science, 2013
The aim of this study was to determine metal ions (bismuth(III), cadmium (II) and lead (II)) using differential pulse voltammetry in the sample of Sosedka pegmatite. Primarily, we characterized rock composition using electron microscopy.
Dana Fialova, Monika Kremplova, David Hynek, Marie Konecna, Jozef Kaiser, Radomír Malina, Jindrich Kynicky, Olga Krystofova, Rene Kizek, Vojtech Adam   +9 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

European Union Agencies

, 2021
The institutional development of European Union (EU) agencies is striking. Over the past decades, forty-six EU agencies have been established to support the European Commission and member states in their regulatory and executive tasks. Today, EU agencies are a vital part of the EU’s administrative capacity.
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Using of Paramagnetic Microparticles and Quantum Dots for Isolation and Electrochemical Detection of Influenza Viruses’ Specific Nucleic Acids

International Journal of Electrochemical Science, 2013
The aim of this study was to suggest isolation protocol based on paramagnetic microparticles and multicolour electrochemical detection of three various influenza oligonucleotides (H1N1 influenza subtype, H3N2 influenza subtype and H5N1 influenza subtype)
Ludmila Krejcova, Dalibor Huska, David Hynek, Pavel Kopel, Vojtech Adam, Jaromir Hubalek, Libuse Trnkova, Rene Kizek   +7 more
doaj   +1 more source