Results 71 to 80 of about 354,025 (268)
Femtogram Electroanalytical Detection of Prostatic Specific Antigen by Brdicka Reaction
International Journal of Electrochemical Science, 2012 Prostatic-specific antigen is considered as the best marker for prostate cancer. Due to the importance of PSA for diagnostic purposes it is not surprising that there are tested and optimized various methods for its determination.
David Hynek +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
International Journal of Electrochemical Science, 2013 Due to threat coming from viral diseases, mainly from influenza, new assays and devices are investigated. This study is aimed at developing of low-cost isolation and detection of specific influenza protein hemagglutinin (HA) labelled with CdS, PbS, and ...
Dana Fialova +14 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
International Journal of Electrochemical Science, 2016 Zinc, an essential element playing crucial roles in numerous physiological, but also pathological processes, is still one of the most studied elements.
Jorge Molina-López +9 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
International Journal of Electrochemical Science, 2012 Doxorubicin is a known anticancer drug intercalating into dsDNA. The mechanism of interaction of doxorubicin with ssDNA is not clear. In this study, adsorptive transfer stripping technique coupled with square wave voltammetry was used for studying of ...
David Hynek +9 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
International Journal of Electrochemical Science, 2012 Interaction of low molecular weight compounds with DNA is one of general mechanisms utilized for an effective anticancer therapy. The anthracycline doxorubicin is one of the drugs that represent the compound with such effect.
David Hynek +9 more
doaj +1 more source
European communion: political theory of European union [PDF]
Journal of European Public Policy, 2012 Political theory of European union, through an engagement between political concepts and theoretical understandings, provides a means of identifying the EU as a political object. It is argued that understanding the projects, processes and products of European union, based on ‘sharing’ or ‘communion’, provides a better means of perceiving the EU as a ...
openaire +4 more sources