Results 71 to 80 of about 2,761,709 (313)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

"The Impact of EU's Cultural Activities on Establishing a European Identity" [PDF]

open access: yes, 2000
European integration has historically been concerned with economic and commercial benefits, but now the aim is to take it further, starting with a broader base capable of involving citizens to a greater degree and strengthening the feeling of belonging ...
Kouveliotis, Kyriakos.
core  

European Union Litigation

open access: yesEuropean Review of Contract Law, 2017
Abstract This article provides an overview of cases decided by the Court of Justice of the European Union concerning contract law. The present issue covers the period between the beginning of July 2019 and the end of December 2019.
ESPOSITO, Fabrizio, HACKER, Philipp
openaire   +4 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

European Union Funds – Application Perspective

open access: yesStudia Europejskie
The result of an effective management of the redistribution of European Union funds should be a reduction of disparities between EU regions by guaranteeing their comprehensive and harmonious development and supporting the economic and social cohesion of ...
Przemysław Dubel, Julita Majczyk
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Sosedka Pegmatite Metal Ions Composition Determined by Voltammetry

open access: yesInternational Journal of Electrochemical Science, 2013
The aim of this study was to determine metal ions (bismuth(III), cadmium (II) and lead (II)) using differential pulse voltammetry in the sample of Sosedka pegmatite. Primarily, we characterized rock composition using electron microscopy.
Dana Fialova   +9 more
doaj   +1 more source

Taxes in Europe Database [PDF]

open access: yes
The Taxes in Europe database is the European Commission's on-line information tool covering the main taxes in force in the EU Member States. Access is free for all users.
European Commission DG Taxation and Customs Union
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

ACL injury prevention in European women’s football: exploring knowledge, attitudes and practices in a cross-sectional study

open access: yesBMJ Open Sport & Exercise Medicine
Objective To assess the knowledge, attitudes and behaviours regarding anterior cruciate ligament (ACL) injury prevention among individuals involved in women’s football at all levels, including players and staff across Union of European Football ...
Evert Verhagen   +2 more
doaj   +1 more source

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