Results 81 to 90 of about 2,626,403 (362)
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Organic Farming and Market Development in Europe and the European Union [PDF]
, 2018 In this chapter, the 2016 data on the organic sector in Europe and the European Union are summarized. The development of the European and the European Union’s organic sector in 2016 was characterized by two trends. On the one hand, the market showed a
Lernoud, Julia +2 more
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Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Privacy, Expression and the World Wide Web. Shall we Forget? [PDF]
, 2014 Google v Spain is an important judgment of the Court of Justice of the European Union which has important implications for the rights of individuals’ privacy, the Court’s use of a purposive method of interpretation, the regulation of search engines ...
Ferris, Katy
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Global PediatricsThe present article introduces the special issue “EPA-UNEPSA Hot Topics in Europaediatrics 2023″ published in the journal Global Pediatrics, which includes articles authored by leading pediatric experts on significant selected topics discussed upon ...
Massimo Pettoello-Mantovani +2 more
doaj
Political Support at EU Level for Energy and Environmental Policies [PDF]
Romanian Journal of European Affairs, 2019 In a context of ever more complex decision-making at the EU level, it is important to understand the underpinnings of consensus for major policies. Building upon the recent experience of the Romanian Presidency of the Council of the European Union, and ...
Clara Volintiru +3 more
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Legal Education and the Role of the Lawyer in the Soviet Union and the Countries of Eastern Europe [PDF]
, 1960 G. M. Razi
openalex +1 more source
The foreign-born population in the European Union and its contribution to national tax and benefit systems : some insights from recent household survey data [PDF]
Despite the purported surge in internal migration following the 2004 enlargement of the European Union, data from the 2006 European Union Survey of Income and Living Conditions show that internal migrants are a relatively small share of the European ...
Barbone, Luca +2 more
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