Results 11 to 20 of about 260 (130)

Production of eurycomanone from cell suspension culture of Eurycoma longifolia [PDF]

Pharmaceutical Biology, 2017
Context: Eurycomanone is found in the Eurycoma longifolia Jack (Simaroubaceae) tree, exhibits significant antimalarial activity, improves spermatogenesis, suppresses expression of lung cancer cell tumour markers and regulates signalling pathways involved
Nguyen Huu Nhan, Nguyen Hoang Loc
doaj   +5 more sources

Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53 [PDF]

Cancer Cell International, 2009
Background Eurycomanone is a cytotoxic compound found in Eurycoma longifolia Jack. Previous studies had noted the cytotoxic effect against various cancer cell lines.
Zakaria Yusmazura, Rahmat Asmah, Pihie Azimahtol, Abdullah Noor, Houghton Peter J   +4 more
doaj   +3 more sources

Eurycomanone stimulates bone mineralization in zebrafish larvae and promotes osteogenic differentiation of mesenchymal stem cells by upregulating AKT/GSK-3β/β-catenin signaling

Journal of Orthopaedic Translation, 2023
Background: Eurycomanone (EN) is a diterpenoid compound isolated from the roots of Eurycoma longifolia (E. longifolia). Previous studies have confirmed that E. longifolia can enhance bone regeneration and bone strength.
Bo Wei, Liao Cui
exaly   +3 more sources

Effects of drying temperature on drying kinetics and eurycomanone content of Eurycoma longifolia roots

Food Research, 2017
In this study, the effects of temperature on drying kinetics and eurycomanone content of Eurycoma longifolia roots were investigated to determine the optimum temperature for drying of this herb.
Hada Masayu, I.,, Pin, K.Y.,, Mohd. Nordin, I.,, Rabitah, Z., Mohd Radzi, A.   +4 more
doaj   +2 more sources

Evaluating Eurycomanone as a Potential Antiviral Agent Against SARS-CoV-2 Variants

Natural Product Communications
Background SARS-CoV-2 continues to evolve, with new variants showing higher transmissibility and immune evasion. The limited effectiveness of current antiviral drugs highlights the potential of natural product compounds, such as eurycomanone as promising
Norazlan Mohmad Misnan, Nur Hannani Ahmad Rozani, Fatahiya Mohamed Tap, Maizatul Hasyima Omar, Kok Wai Lam, Mohd Ridzuan Mohd Abd Razak   +5 more
doaj   +2 more sources

Assessing product adulteration of Eurycoma longifolia (Tongkat Ali) herbal medicinal product using DNA barcoding and HPLC analysis [PDF]

Pharmaceutical Biology, 2018
Context: Eurycoma longifolia Jack (Simaroubaceae) commonly known as Tongkat Ali is one of the most important plants in Malaysia. The plant extracts (particularly roots) are widely used for the treatment of cough and fever besides having antimalarial ...
Bashir Mohammed Abubakar, Faezah Mohd Salleh, Mohd Shahir Shamsir Omar, Alina Wagiran   +3 more
doaj   +2 more sources

Development of Niosome-Encapsulated Standardized Water Extract of Eurycoma longifolia for Potential Immunomodulatory Activity In Vitro

Journal of Nanotechnology
Eurycoma longifolia is a well-known medicinal plant recognized for its anticancer activity and immunomodulatory properties. Despite its therapeutic potential, the extract has demonstrated low bioavailability, particularly due to the limited permeability ...
Muhammad Nor Farhan Saat, Norazlinaliza Salim, Wan Abdul Hakim Wan Lokman, Nabilah Md Razak, Mohd Basyaruddin Abdul Rahman, Murizal Zainol, Azren Aida Asmawi, Mohd Ridzuan Mohd Abd Razak   +7 more
doaj   +2 more sources

Phytochemicals: Alternative for Infertility Treatment and Associated Conditions. [PDF]

Oxid Med Cell Longev, 2023
Infertility and obstetric complications have become global health issues in the past few years. Infertility is defined as the inability of a couple to conceive even after twelve months or more of regular and unprotected intercourse. According to WHO data published in the year 2020, 186 million people have infertility globally.
Chorosho SH, Malik N, Panesar G, Kumari P, Jangra S, Kaur R, Al-Ghamdi MS, Albishi TS, Chopra H, Singh R, Murthy HCA.   +10 more
europepmc   +2 more sources

Rapid Structural Analysis of Natural Products Using MicroED. [PDF]

Small
The cryoEM method, MicroED used for rapid analysis and structure determination of natural products that remained unattainable by other structural biology methods ABSTRACT Structural analysis of natural products remains challenging due to their inherent complexity and limited availability.
Lin J, Paz O, Unge J, Gonen T.
europepmc   +2 more sources

A Systematic Review on Antimicrobial and Antiparasitic Activity of <i>Eurycoma longifolia</i> Jack (Tongkat Ali). [PDF]

Biomed Res Int, 2022
Eurycoma longifolia or Tongkat Ali (family: Simaroubaceae) has the potential to be utilised as an antimicrobial and antiparasitic agent that correlated with its traditional use to treat jaundice, malaria, antiseptic agent, and many more. This review is aimed at systematically sieving through articles regarding the antimicrobial and antiparasitic ...
Latip MQA, Noor MHM, Ahmad H, Hassim HA, Salleh A, Bejo MH, Zakaria AA.   +6 more
europepmc   +2 more sources