Results 21 to 30 of about 260 (130)

Cytotoxicity of Eurycomanone and Fargesin in RAW 264.7 Murine Macrophages

open access: yesJournal of Pharmaceutical Research International, 2021
Bioactive natural compounds derived from plants are the source for the development of new drugs. Numerous in vitro studies have explored the anti-inflammatory effect of eurycomanone and fargesin, derived from Eurycoma longifolia and Flosmagnoliae, respectively.
Hasseri Halim   +6 more
openaire   +2 more sources

Development of combinative method using HPLC fingerprints and quantitative analysis for quality assessment of Chantaleela preparation [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2021
Chantaleela (CTL) is a Thai traditional medicine composed of 8 medicinal herbs and borneol and used to treat fever. This study aimed to control the quality of CTL products by establishing a simple but comprehensive method using high performance liquid ...
Dujhathai Anekchai, Athip Sakunphueak
doaj   +1 more source

Simultaneous quantification of eurycomanone, epimedin C and icariin in film coated tablets containing Radix Eurycomae longifoliae extract and Herba Epimedii extract using HPLC – DAD [PDF]

open access: yesPharmacia, 2021
Introduction. This study aimed at developing an HPLC-DAD method for simultaneous determination of eurycomanone (EU), epimedin C (EC) and icariin (IC) in EE tablets containing Radix Eurycomae longifoliae extract and Herba Epimedii extract (EE tablets).
Huynh Tran Quoc Dung   +4 more
doaj   +3 more sources

A Brief Review of Natural Products with Urate Transporter 1 Inhibition for the Treatment of Hyperuricemia

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Hyperuricemia is a common disease caused by a high level of uric acid. Urate transporter 1 (URAT1) is an important protein and mediates approximately 90% of uric acid reabsorption. Therefore, the URAT1 inhibitor is a class of uricosuric medicines widely used in the clinic for the treatment of hyperuricemia.
Qianghua Yuan   +5 more
wiley   +1 more source

Identification of Phytochemicals from the Water Extract of Eurycoma longifolia Roots using Solid-Liquid and Liquid-Liquid Extraction Based Fractionation Techniques

open access: yesActa Chimica Slovenica, 2021
Phytochemicals in the water extract of Eurycoma longofolia roots were identified using both solid-liquid and liquid-liquid extraction based fractionation techniques.
Lee Suan Chua   +2 more
doaj   +1 more source

Unfermented Freeze‐Dried Leaf Extract of Tongkat Ali (Eurycoma longifolia Jack.) Induced Cytotoxicity and Apoptosis in MDA‐MB‐231 and MCF‐7 Breast Cancer Cell Lines

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
The present study was conducted to determine the cytotoxicity effect of Eurycoma longifolia (Jack.) leaf extracts and also its possible anticancer mechanism of action against breast cancer cell lines: non‐hormone‐dependent MDA‐MB‐231 and hormone‐dependent MCF‐7. The leaves of E.
Lusia Barek Moses   +4 more
wiley   +1 more source

Eurycomanone regulates lipid metabolism by activating the cAMP/PKA pathway [PDF]

open access: yes, 2020
Abstract Eurycoma longifolia Jack (ELJ) contains mainly alkaloids, and quassinoids, which are the main active ingredients. Eurycomanone (EN), one of the most common quassinoids, is said to have beneficial effects on lipid and glucose metabolism.
Zhihui Jiang   +8 more
openaire   +1 more source

Rho-Kinase II Inhibitory Potential of Eurycoma longifolia New Isolate for the Management of Erectile Dysfunction. [PDF]

open access: yesEvid Based Complement Alternat Med, 2019
Background. Eurycoma longifolia Jack (Fam.: Simaroubaceae), known as Tongkat Ali (TA), has been known as a symbol of virility and sexual power. The aim of the study was to screen E. longifolia aqueous extract (AE) and isolates for ROCK‐II inhibition. Results.
Ezzat SM   +4 more
europepmc   +2 more sources

Isolation and lipolytic activity of eurycomanone and its epoxy derivative from Eurycoma longifolia [PDF]

open access: yesBioorganic & Medicinal Chemistry, 2017
Eurycomanone (1) and 13β,21-epoxyeurycomanone (2) were isolated from Eurycoma longifolia for studies of lipolytic activity. Compound 1 enhanced lipolysis in adipocytes with an EC50 of 14.6μM, while its epoxy derivate, compound 2, had a stronger activity with an EC50 of 8.6μM.
Lahrita, Lucy   +3 more
openaire   +3 more sources

Evaluation of anti-inflammatory properties of Eurycoma longifolia Jack and Eurycoma harmandiana Pierre in vitro cultures and their constituents

open access: yesFood and Agricultural Immunology, 2022
Eurycoma longifolia Jack (EL) has been used for treating erectile dysfunction, in which inflammation plays a major role. EL tissue cultures can overcome the shortage of material; however, the anti-inflammatory property of such cultures has not been ...
Jiranan Chaingam   +5 more
doaj   +1 more source

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