Results 21 to 30 of about 260 (130)
Cytotoxicity of Eurycomanone and Fargesin in RAW 264.7 Murine Macrophages
Bioactive natural compounds derived from plants are the source for the development of new drugs. Numerous in vitro studies have explored the anti-inflammatory effect of eurycomanone and fargesin, derived from Eurycoma longifolia and Flosmagnoliae, respectively.
Hasseri Halim +6 more
openaire +2 more sources
Development of combinative method using HPLC fingerprints and quantitative analysis for quality assessment of Chantaleela preparation [PDF]
Chantaleela (CTL) is a Thai traditional medicine composed of 8 medicinal herbs and borneol and used to treat fever. This study aimed to control the quality of CTL products by establishing a simple but comprehensive method using high performance liquid ...
Dujhathai Anekchai, Athip Sakunphueak
doaj +1 more source
Simultaneous quantification of eurycomanone, epimedin C and icariin in film coated tablets containing Radix Eurycomae longifoliae extract and Herba Epimedii extract using HPLC – DAD [PDF]
Introduction. This study aimed at developing an HPLC-DAD method for simultaneous determination of eurycomanone (EU), epimedin C (EC) and icariin (IC) in EE tablets containing Radix Eurycomae longifoliae extract and Herba Epimedii extract (EE tablets).
Huynh Tran Quoc Dung +4 more
doaj +3 more sources
Hyperuricemia is a common disease caused by a high level of uric acid. Urate transporter 1 (URAT1) is an important protein and mediates approximately 90% of uric acid reabsorption. Therefore, the URAT1 inhibitor is a class of uricosuric medicines widely used in the clinic for the treatment of hyperuricemia.
Qianghua Yuan +5 more
wiley +1 more source
Phytochemicals in the water extract of Eurycoma longofolia roots were identified using both solid-liquid and liquid-liquid extraction based fractionation techniques.
Lee Suan Chua +2 more
doaj +1 more source
The present study was conducted to determine the cytotoxicity effect of Eurycoma longifolia (Jack.) leaf extracts and also its possible anticancer mechanism of action against breast cancer cell lines: non‐hormone‐dependent MDA‐MB‐231 and hormone‐dependent MCF‐7. The leaves of E.
Lusia Barek Moses +4 more
wiley +1 more source
Eurycomanone regulates lipid metabolism by activating the cAMP/PKA pathway [PDF]
Abstract Eurycoma longifolia Jack (ELJ) contains mainly alkaloids, and quassinoids, which are the main active ingredients. Eurycomanone (EN), one of the most common quassinoids, is said to have beneficial effects on lipid and glucose metabolism.
Zhihui Jiang +8 more
openaire +1 more source
Rho-Kinase II Inhibitory Potential of Eurycoma longifolia New Isolate for the Management of Erectile Dysfunction. [PDF]
Background. Eurycoma longifolia Jack (Fam.: Simaroubaceae), known as Tongkat Ali (TA), has been known as a symbol of virility and sexual power. The aim of the study was to screen E. longifolia aqueous extract (AE) and isolates for ROCK‐II inhibition. Results.
Ezzat SM +4 more
europepmc +2 more sources
Isolation and lipolytic activity of eurycomanone and its epoxy derivative from Eurycoma longifolia [PDF]
Eurycomanone (1) and 13β,21-epoxyeurycomanone (2) were isolated from Eurycoma longifolia for studies of lipolytic activity. Compound 1 enhanced lipolysis in adipocytes with an EC50 of 14.6μM, while its epoxy derivate, compound 2, had a stronger activity with an EC50 of 8.6μM.
Lahrita, Lucy +3 more
openaire +3 more sources
Eurycoma longifolia Jack (EL) has been used for treating erectile dysfunction, in which inflammation plays a major role. EL tissue cultures can overcome the shortage of material; however, the anti-inflammatory property of such cultures has not been ...
Jiranan Chaingam +5 more
doaj +1 more source

