Results 201 to 210 of about 218,220 (306)

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

Epilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden, Verena Buchecker, Amelie Wagner, Victoria M. Stocker, Liga Zvejniece, Heidrun Potschka   +5 more
wiley   +1 more source

On the topical issue of assisted dying: the insurmountable challenges of human existence, and the right to exit. [PDF]

Front Public Health
Tobore TO.
europepmc   +1 more source

Calcitonin gene‐related peptide concentration in cerebrospinal fluid and serum in horses affected by trigeminal‐mediated headshaking

Equine Veterinary Journal, EarlyView.
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber, Hilke Oltmanns, Ludovica Chiavaccini, Kirstie J. Pickles, Veronica Roberts, Tanja Kloock, Tobias Niebuhr, Karsten Feige   +7 more
wiley   +1 more source

Willingness of Dutch general practitioners to grant euthanasia and assisted suicide requests: a comparative study of physical and mental health conditions. [PDF]

BMC Med Ethics
Jenniskens EPGM, Mevenkamp N.
europepmc   +1 more source

Euthanasia and Brain Death: Ethical and Legal Considerations [PDF]

, 1978
Horan, Dennis J.
core   +1 more source

Development of the Human–Equine Attachment Scale

Equine Veterinary Journal, EarlyView.
Abstract Background Human–horse relationships encompass diverse roles, from companion to competition partner. The impact of such bonds informs owner decision‐making regarding horse management and veterinary care, yet standardised instruments to measure these unique bonds are limited.
Richard H. Corrigan, Marc Pierard, Emma Davies, David Marlin, Stephanie Evans, Jane M. Williams   +5 more
wiley   +1 more source

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation. [PDF]

Equine Vet J
Schliewert EC, Hooijberg EH, Goddard A.
europepmc   +1 more source

[Book Review of] \u3cem\u3eThe Singer-Affaire\u3c/em\u3e, by Hiram Caton, D.Litt., Director, The Bonhoeffer Institute [PDF]

, 1991
Catholic Physicians\u27 Guild
core   +1 more source

VOLUNTARY EUTHANASIA [PDF]

American Journal of Public Health and the Nations Health, 1932
openaire   +2 more sources

Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review

Equine Veterinary Journal, EarlyView.
Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska, Bernard Turek, Tomasz Jasiński, Michał Kaczorowski, Natalia Kozłowska, Julia Higuchi, Małgorzata Domino   +6 more
wiley   +1 more source