Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng +7 more
wiley +1 more source
StrayCare Metro: Evaluation of a Targeted Cat Desexing Program to Manage Free-Roaming Cats. [PDF]
Ma GC, Zito S, Kennedy BPA.
europepmc +1 more source
Field samples from breeder duck farms with egg‐production decline were subjected to viral detection, genome sequencing, and virus isolation. Experimental infection demonstrated that duck orbivirus (DORV) causes a significant and persistent reduction in egg production in breeder ducks.
Bing Li +18 more
wiley +1 more source
CO and N<sub>2</sub> are not humane alternatives to CO<sub>2</sub> euthanasia in rats. [PDF]
Calvet C +8 more
europepmc +1 more source
Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis +11 more
wiley +1 more source
Development and Psychometric Properties of PEACE-Q: A Questionnaire on Attitudes Towards Physician-Assisted Dying, Euthanasia, Advance Directives and Care at the End-of-Life. [PDF]
Koulouras V +4 more
europepmc +1 more source
Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra +8 more
wiley +1 more source
Retraction: A fine balance of dietary lipids improves pathology of a murine model of VCP-associated multisystem proteinopathy. [PDF]
PLOS One Editors.
europepmc +1 more source
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source

