Results 231 to 240 of about 164,007 (300)

Extraintestinal Reprogramming of Colon‐Derived CD4+ Intraepithelial Lymphocytes Reveals a Mechanism Underlying the Gut–Joint Axis

Arthritis &Rheumatology, EarlyView.
Objective The gut–joint axis is a central paradigm in spondyloarthritis, yet the cellular mechanisms linking intestinal and joint immunity remain poorly understood. One potential link is T cell receptor αβ+ CD4+ colon intraepithelial lymphocytes (cIELs) that can traffic to extraintestinal tissues, including the joint.
Sarah M. Danielson, Connor Eck, Sucai Liu, Anna Helena Jonsson, Kristine A. Kuhn   +4 more
wiley   +1 more source

Multicentre aortic thromboembolism thrombolysis evaluation in a retrospective study of 183 cats: the MATTERS study. [PDF]

Front Vet Sci
Cambournac M, Damoiseau C, Guillaumin J, Goy-Thollot I, Pouzot-Nevoret C.   +4 more
europepmc   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Equine dystocia in Sweden (2006-2022): a retrospective analysis of mare and foal survival. [PDF]

Front Vet Sci
Verbruggen M, Morrell JM, Wessel M, Olsson E, Ntallaris T.   +4 more
europepmc   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Correction: Khourcha et al. Assessing the Efficacy of Monovalent and Commercialized Antivenoms for Neutralizing Moroccan Cobra <i>Naja haje</i> Venom: A Comparative Study. <i>Trop. Med. Infect. Dis.</i> 2023, <i>8</i>, 304. [PDF]

Trop Med Infect Dis
Khourcha S, Hilal I, Elbejjaj I, Karkouri M, Safi A, Hmyene A, Oukkache N.   +6 more
europepmc   +1 more source

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

Reframing emergency preparedness from facility survival to laboratory animal welfare. [PDF]

Lab Anim Res
Kim SY, Lee JM, Seok SH.
europepmc   +1 more source