Results 81 to 90 of about 210,115 (312)
Advanced Science, EarlyView.An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang +10 more
wiley +1 more source
Planning for the End of Life for People with Dementia - Part 2 [PDF]
, 2011 This publication is a discussion about additional end-of-life options which may become legally available at some time in the future, i.e., assisted death (usually called euthanasia or assisted suicide).
Colleen Cartwright
core +1 more source
Advanced Science, EarlyView.This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren +11 more
wiley +1 more source
Advanced Science, EarlyView.This manuscript presents a carrier‐free nanomedicine PCNPs@PEG‐Man with dual‐targeting for IBD. It resists harsh intestinal conditions, reduces oxidative stress, enhances drug uptake and retention, modulates inflammation, and reshapes gut microbiota, offering a safe and effective IBD therapy.
Yingjie Chen +8 more
wiley +1 more source
Poultry Science, 2022 : Efficacious euthanasia by applying manual cervical dislocation can be difficult on large and mature poultry. The challenge with using manual cervical dislocation is that the strength required to hold heavy poultry and swiftly apply cervical dislocation
R.S. Boyal +4 more
doaj
Animals, 2018 Using euthanasia to manage dog and cat overpopulation causes health issues and emotional stress in employees involved, increases staff turnover, and has financial, moral and ethical ramifications for communities.
Jacquie Rand +4 more
doaj +1 more source
Advanced Science, EarlyView.Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge +10 more
wiley +1 more source
Aspects of Euthanasia in Criminal Law [PDF]
Societas et Iurisprudentia, 2018 The question of euthanasia and its impunity raises many legal and moral issues which are not answered. The intention of this paper is not to express an opinion about suitability or morality of euthanasia or assisted suicide and it also does not contain ...
Vladimíra Dercová
doaj
Advanced Science, EarlyView.Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan +14 more
wiley +1 more source