Results 91 to 100 of about 160,752 (259)
Advanced Science, EarlyView.A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong +13 more
wiley +1 more source
Final Report of the Netherlands State Commission on Euthanasia: An English Summary
, 1987 An unofficial summary is provided of the Final Report of the Netherlands State Commission on Euthanasia, submitted to the Minister of Welfare, Health and Cultural Affairs and the Minister of Justice on 19 Aug 1985.
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Intensive Care Unit Nurses? Opinions About Euthanasia
, 2007 This study was conducted to gain opinions about euthanasia from nurses who work in intensive care units. The research was planned as a descriptive study and conducted with 186 nurses who worked in intensive care units in a university hospital, a public ...
Kumas, Gülsah +2 more
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Advanced Science, EarlyView.Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source
Euthanasia in the Netherlands: Distinguishing Facts From Fiction
, 1989 Doctors practicing euthanasia in the Netherlands do so in violation of the law; however, they will not be prosecuted if they appear to have followed strict guidelines handed down by the Dutch judicial system.
Rigter, Henk
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Advanced Science, EarlyView.IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou +11 more
wiley +1 more source
Euthanasia: Above Ground, Below Ground
, 2004 The key to the euthanasia debate lies in how best to regulate what doctors do. Opponents of euthanasia frequently warn of the possible negative consequences of legalising physician assisted suicide and active euthanasia (PAS/AE) while ignoring the covert
Magnusson, R.S.
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Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
, 1980 The study was designed to compare and contrast responses of two groups of nurses to situational case studies relative to death and dying, with particular emphasis on euthanasia.
Babcock, Patricia Ann
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, 1992 I have cited both good and bad consequences that have been thought likely from a policy change permitting voluntary active euthanasia, and have tried to evaluate their likelihood and relative importance.
Brock, Dan W.
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