Results 81 to 90 of about 160,752 (259)

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

KESESUAIAN PENERAPAN EUTHANASIA TERHADAP PASIEN KONDISI TERMINAL ATAS PERSETUJUAN KELUARGA DALAM HUKUM POSITIF INDONESIA

IBLAM Law Review
Normatively, the act of euthanasia in Indonesia is prohibited because in the Criminal Code it’s classified as a criminal offence as it means deprivation of the patient's life.
Mochammad Alwi Fachrezi, Tomy Michael
doaj   +1 more source

Euthanasia - Choice and Death

, 2005
Euthanasia has become increasingly contentious as populations age, and medical and scientific advances continue to transform and extend life. Euthanasia - Choice and Death examines the key philosophical arguments that have underpinned thinking and ...
Tulloch, Gail
core  

Active Euthanasia in the Netherlands

, 1989
A Dutch bioethicist discusses the status of voluntary, active euthanasia as it is practiced currently in the Netherlands, and traces the medical, legal, and public policy developments in the issue from the early 1970s to the late 1980s.
de Wachter, Maurice A.M., de Wachter, M.A.M.   +1 more
core   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Non‐Line‐of‐Sight Passive Ammonia Sensor Loaded With MXene/In2O3 Composites for Agricultural Products Quality Deterioration Detection

Advanced Science, EarlyView.
This study presents a flexible, battery‐free passive RFID sensing platform for NLoS monitoring of quality deterioration in fresh agricultural products. It utilizes a structurally decoupled spiral antenna‐LC electrode architecture to suppress electromagnetic interference caused by packaging.
Guoping Hu, Lin He, Fanli Meng, Daming Dong, Guolong Shi   +4 more
wiley   +1 more source

A Case Against Dutch Euthanasia

, 1989
The growing acceptance of voluntary active euthanasia by the Dutch is examined in relation to the plastic cards requesting active euthanasia carried by many people in The Netherlands, public opinion polls, and support by leading medical figures of the ...
Fenigsen, Richard
core   +1 more source

Label‐Free Myelin Fingerprinting: An Adult Human Post‐Mortem Brain Slice Platform via Coherent Anti‐Stokes Raman Spectroscopy

Advanced Science, EarlyView.
A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki, Jeroen P. Korterik, Femke Tjebbes, Geert J. Schenk, Herman L. Offerhaus, Antonio Luchicchi   +5 more
wiley   +1 more source

Factors associated with behavioral euthanasia in pet dogs

Frontiers in Veterinary Science
When pet dogs demonstrate certain serious problem behaviors, this may lead owners to choose behavioral euthanasia. However, research on behavioral euthanasia of pet dogs is sparse and previously published papers have not specifically sampled owners who ...
Miranda Hitchcock, Miranda K. Workman, Adeline P. Guthrie, Audrey Ruple, Erica N. Feuerbacher   +4 more
doaj   +1 more source

Euthanasia Across the North Sea

, 1988
The United Kingdom and the Netherlands are separated by a narrow stretch of sea but in terms of an understanding of euthanasia they seem to be light years apart. An attempt to bridge the information gap seems in order.
Borst-Eilers, Els, Rigter, Henk, Leenen, H.J.J.   +2 more
core   +1 more source