Results 121 to 130 of about 337,152 (297)
Epidemiological investigation of euthanasia in an Ontario animal shelter
, 2017 Objectives The objective was to evaluate factors associated with euthanasia in an animal shelter in Kitchener-Waterloo, Ontario, Canada. Methods Data from 3737 cats admitted to the shelter between January and December 2011 were evaluated. Results Overall,
David L Pearl +3 more
core +1 more source
Advanced Science, EarlyView.Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu +13 more
wiley +1 more source
Black oil sunflower seed ingestion and suspected acute lipid toxicity in 4 alpacas
Veterinary and Animal ScienceFour adult female alpacas from the same property in Loomis, CA developed clinical signs of recumbency, lethargy, anorexia, and had abdominal pain at least 48 h after incidental ingestion of a large volume of black oil sunflower seeds.
Chelsea C. Pulter +4 more
doaj +1 more source
Sacrificed, Killed, or Euthanized [PDF]
https://openworks.mdanderson.org/word2024/1001/thumbnail ...
Ninetto, Amy
core
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Advanced Science, EarlyView.Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen +19 more
wiley +1 more source
Lung histopathology observed in mice following exposure to aerosolized B. pseudomallei K96243.
, 2017 (A) C57BL/6 mouse euthanized on day 2 post-infection. Lung: Multifocal random (embolic) suppurative pneumonia. H&E 20X. (B) BALB/c mouse euthanized on day 4 post-infection. Lung: Suppurative inflammation and alveolar necrosis with numerous short bacilli (
Kristen A. Fritts (3779182) +15 more
core +1 more source
Advanced Science, EarlyView.This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha +5 more
wiley +1 more source
Veterinary Medicine: Research and Reports, 2019 Paulina Escandon,1,2 J Jill Heatley,1,3 Ian Tizard,1,2 Jianhua Guo,1,2 HL Shivaprasad,4 Jeffrey MB Musser1,2 1Schubot Exotic Bird Health Center, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843, USA; 2Department of ...
Escandon P +5 more
doaj
Histopathology observed in mice following IP challenge with B. pseudomallei K96243.
, 2017 (A) C57BL/6 mouse euthanized on day 2 post-infection Liver: Random foci of neutrophilic inflammation with individual hepatocyte necrosis/apoptosis (arrow). I = inflammation; H&E, 400X.
Kristen A. Fritts (3779182) +15 more
core +1 more source