Results 71 to 80 of about 337,152 (297)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Comparative Study of Montelukast with Dexamethasone for Possible Protection against Endotoxic Effect of Lipopolysaccharide in Male Mice

Iraqi Journal of Pharmaceutical Sciences
Endotoxic septic shock (ESS) is a serious clinical syndrome caused by gram-negative bacterial infections. ESS refers to infected patients with high bloodstream endotoxin levels and activity and a high rate of cardiovascular, pulmonary, hepatic, and ...
Rami Isam Kamal Alsaati, Ahmed Hamed Jwaid   +1 more
doaj   +1 more source

Effect of Nandrolone Decanoate on Some Biochemical Markers When Used as Adjuvant Therapy for Healing of Facial Muscle Wound [PDF]

Al-Rafidain Dental Journal
Aims: to distinguish if the nanodrolone decanoate has any effect on the healing of facial muscular wounds which are one of the issues that dentists face, and it is a challenge to find a useful treatment for this condition.
Tamarah M. Al-Abdullah, Faehaa A. Al-Mashhadane   +1 more
doaj   +1 more source

Implantable Ionic Memristors Based on Natural Polymer Heterojunctions

Advanced Functional Materials, EarlyView.
We report an implantable natural polymer‐based ionic memristor composed of hyaluronic acid, chitosan, and PDMS. The device achieved 98.94% accuracy in MNIST classification while reducing training time by 36.8% compared with a conventional artificial neural network (ANN).
Dong‐yup Lee, Byung Ik Park, Gihyeon Yim, Hyunjae Yoo, Sangjun Ma, Jundong Park, Jeong‐Yun Sun   +6 more
wiley   +1 more source

Cervical Physeal dysplasia and subchondral synovial cyst in a case of compressive myelopathy in a six-year-old Warmblood gelding

Brazilian Journal of Veterinary Pathology
A 6-year-old, 604 kg. History of progressive incoordination, difficulty to jump and ataxia. Euthanized with barbituric overdose.
Miguel Carrillo Parraguez, Brian Murphy, Nick Huggons, Francisco R. Carvallo   +3 more
doaj   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

THE PARADOX OF EUTHANIZING KOALAS (PHASCOLARCTOS CINEREUS) TO SAVE POPULATIONS FROM ELIMINATION

Journal of Wildlife Diseases, 2015
Koala (Phascolarctos cinereus) populations in the wild are in sharp decline in Australia due to deforestation, road accidents, dog attacks, and disease from infection with sexually transmitted Chlamydia spp. Severely diseased koalas that are captured are euthanized for humane reasons because antibiotics are not effective. Paradoxically, we propose that
Wilson, David P, Craig, Andrew P, Hanger, Jon, Timms, Peter   +3 more
openaire   +3 more sources

Spatial cluster analysis of dogs euthanized due to severe health issues or behavioral issues within dog intake data from Athens-Clarke County Animal Control, Athens-Clarke County, GA, by overall social vulnerability index (SVI), 2014–2016.

, 2019
Spatial cluster analysis of dogs euthanized due to severe health issues or behavioral issues within dog intake data from Athens-Clarke County Animal Control, Athens-Clarke County, GA, by overall social vulnerability index (SVI), 2014–2016.
Jessie L. Dyer (8067185), Lisa Milot (8067188)   +1 more
core   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Canine Euthanasia’s Trend Analysis during Thirty Years (1990–2020) in Italy: A Veterinary Hospital as Case Study

Veterinary Sciences
This study aimed to investigate changes in the number of, and reasons for, requests for dogs’ euthanasia over the last thirty years. Data (breed, age, gender, neuter status, manner, and cause of death) from dogs’ euthanasia registered between 1990 and ...
Annalisa Previti, Vito Biondi, Michela Pugliese, Angela Alibrandi, Agata Zirilli, Mariana Roccaro, Angelo Peli, Annamaria Passantino   +7 more
doaj   +1 more source