Epidemiology and clinical manifestations of different enterovirus and rhinovirus types show that EV-D68 may still have an impact on severity of respiratory infections. [PDF]
J Med Virol, 2022 Larsson SB +4 more
europepmc +1 more source
Characterization of possible binding of loxapine to the EV-D68 2C hexamer.
(A) Distribution of binding energies of the top-100 binding poses of the structure of the EV-D68 2C-loxapine complex. Line indicates mean value. (B) Binding mode between EV-D68 2C and loxapine in the top-1 model of in silico docking simulation.
Masaru Yokoyama (53773) +9 more
core +1 more source
Respiratory and intestinal epithelial cells exhibit differential susceptibility and innate immune responses to contemporary EV-D68 isolates. [PDF]
Elife, 2021 Freeman MC +6 more
europepmc +1 more source
Neutralizing Antibody Given after Paralysis Onset Reduces the Severity of Paralysis Compared to Nonspecific Antibody-Treated Controls in a Mouse Model of EV-D68-Associated Acute Flaccid Myelitis. [PDF]
Antimicrob Agents Chemother, 2022 Rudy MJ, Frost J, Clarke P, Tyler KL.
europepmc +1 more source
Simultaneous enterovirus EV-D68 and CVA6 infections causing acute respiratory distress syndrome and hand, foot and mouth disease. [PDF]
Virol J, 2021 de Sousa IP +6 more
europepmc +1 more source
Introduction Non-polio enteroviruses, particularly EV-D68 and EV-A71, have emerged as major pediatric threats due to their association with acute flaccid myelitis and high mortality.
Bor-Luen Chiang +4 more
core +1 more source
Community acquired acute respiratory infections caused by enterovirus D68 (EV-D68)
Anales de Pediatría (English Edition), 2017 Jordi, Reina +2 more
openaire +2 more sources
Live Virus EV-D68 - on RD cells - Antiviral Screening Assay v1
The following is a protocol for live virus antiviral screening against EV-D68 in vitro on Rhabdomyosarcoma (RD) cells. RD Cells are prophylactically treated with antiviral candidates that have been serially diluted to investigate activity. IC50 values are generated via analysis of MTT/MTS data as a readout of CPE (cytopathic effect).
openaire +1 more source
European surveillance for enterovirus D68 during the emerging North-American outbreak in 2014.
Background: In August and September 2014, unexpected clusters of enterovirus-D68 (EV-D68) infections associated with severe respiratory disease emerged from North-America.
Josset, L. +6 more
core
Enterovirus D68 -- EV-D68 in the United States -- Seasonal Circulation -- Symptoms -- Spread -- Risk -- Diagnosis -- Treatment -- Protection -- Recommendations for those with asthma -- 2014 Outbreak -- Future ...
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