Results 111 to 120 of about 317,847 (188)

Molecular detection of enterovirus D68 among children with acute respiratory tract infection in Ghana

African Journal of Laboratory Medicine, 2019
Background: Acute respiratory tract infections of viral origin remain a leading cause of morbidity, mortality and economic loss regardless of age or gender. A small number of acute respiratory tract infection cases caused by enterovirus D68 (EV-D68) have
Joyce A. Kubi, Mohamed Mutocheluh, Joseph H.K. Bonney, William K. Ampofo, John K. Odoom   +4 more
doaj   +1 more source

Live Virus EV-D68 - RD - Antiviral Screening Assay v1

The following is a protocol for live virus antiviral screening against EV-D68 in vitro using Rhabdomyosarcoma (RD) cells. RD Cells are prophylactically treated with antiviral candidates that have been serially diluted to investigate activity, via IC50 values generated via analysis of immunofluorescent staining, against EV-D68.
Rebecca Pearl, Randy Albrecht
openaire   +1 more source

A cotton rat model of EV-D68 infection and replication.

, 2016
Cotton rats were infected i.n. with 106 TCID50 per rat with 3 different strains of EV-D68, ATCC (prototype Fermon strain), VANBT (2012 pre-outbreak strain from Nashville, TN) and MO/49 (2014 outbreak strain from Kansas, MO). (A) Evolutionary tree showing
Lioubov M. Pletneva (3332703), Marina S. Boukhvalova (3332700), Jorge C. G. Blanco (292565), Mira C. Patel (3332697), Stefanie N. Vogel (172439), Seesandra V. Rajagopala (14615), Wei Wang (17594), Suman R. Das (236651), Yi Tan (160353), Tina V. Hartert (356857)   +9 more
core   +1 more source

Enhanced genomic surveillance of enteroviruses reveals a surge in enterovirus D68 cases, the Johns Hopkins health system, Maryland, 2024

Journal of Clinical Microbiology
This study reports increased Enterovirus D68 (EV-D68) circulation in 2024, re-establishing its biennial circulation cycle after its interruption during the COVID-19 pandemic.
Amary Fall, Julie M. Norton, Omar Abdullah, Andrew Pekosz, Eili Klein, Heba H. Mostafa   +5 more
doaj   +1 more source

Salt-inducible kinase 1 is a key gene in suppressing EVD68-induced asthma by modulating antiviral immunity

Genes and Diseases
Asthma is a complex inflammatory disease of the airways, affecting over 300 million individuals globally. Infection with enterovirus D68 (EV-D68) has been identified as a risk factor for asthma. However, the biological mechanisms of EV-D68-related asthma
Juntong Liu, Yue Wang, Lingyun Zou, Xinyue Han, Mingqi Lv, Xichuan Deng, Jingjing Liao, Guangchao Zang, Lei Xu, Tianle Gu, Nan Lu, Guangyuan Zhang   +11 more
doaj   +1 more source

F-104 Emergence of novel EV-D68 lineages associated with acute flaccid paralysis

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2019
Enterovirus D68 (EV-D68) has historically been associated with respiratory illnesses. However, in the summers of 2014 and 2016, EV-D68 outbreaks coincided with a spike in polio-like acute flaccid myelitis/paralysis (AFM/AFP) cases. This raised concerns that EV-D68 could be the causative agent of AFM during these recent outbreaks.
openaire   +2 more sources

Differences in the proliferative capacities of 2014 Epidemic and Fermon EV-D68 Strains [PDF]

Journal of Allergy and Clinical Immunology, 2018
Nicholas Klaiber, Michael Mcvoy, Wei Zhao   +2 more
openaire   +1 more source

Elucidating the role of human skeletal muscles in the pathogenesis of enterovirus D68 infection

Life Science Alliance
Human skeletal muscles play a more direct role in the pathogenesis of enterovirus D68 through productive infection, which leads to structural destruction, functional loss, and hampered regeneration.
Brigitta M Laksono, Atze J Bergsma, Alessandro Iuliano, Dominique Y Veldhoen, Stefan van Nieuwkoop, Marjan Boter, Lonneke Leijten, Lisa Bauer, Bas B Oude Munnink, WWM Pim Pijnappel, Debby van Riel   +10 more
doaj   +1 more source

EV-D68 virus-like particle vaccines elicit cross-clade neutralizing antibodies that inhibit infection and block dissemination. [PDF]

Sci Adv, 2023
Krug PW, Wang L, Shi W, Kong WP, Moss DL, Yang ES, Fisher BE, Morabito KM, Mascola JR, Kanekiyo M, Graham BS, Ruckwardt TJ.   +11 more
europepmc   +1 more source

Co-circulation of Rhinovirus A and C during the EV-D68 Epidemic Period [PDF]

Open Forum Infectious Diseases, 2017
Amy Callear, Sydney Foote, Hannah E Segaloff, Duane Newton, Nicole S Stroufe, Helena Wang-Flores, Terri Stillwell, Marc Hershenson, Emily T Martin   +8 more
openaire   +1 more source