Results 91 to 100 of about 248,805 (183)

mRNA vaccine expressing enterovirus D68 virus-like particles induces potent neutralizing antibodies and protects against infection

open access: yesMolecular Therapy: Nucleic Acids
Enterovirus D68 (EV-D68) causes respiratory illness in children. It also causes severe paralysis called acute flaccid myelitis (AFM), which has become a global health threat. Here, we generated an mRNA vaccine expressing virus-like particles (VLPs) of EV-
Yuta Kunishima   +4 more
doaj   +1 more source

Incidence trends and disease burden of respiratory syncytial virus (RSV) infection from 2014 to 2019 before the COVID‐19 pandemic in Fukushima, Japan

open access: yesPediatrics International, Volume 67, Issue 1, January/December 2025.
Abstract Background The incidence trends and disease burden of pediatric respiratory syncytial virus (RSV) infection in Japan have yet to be fully elucidated. Methods With the cooperation of all 16 pediatric inpatient facilities in Fukushima Prefecture, we prospectively investigated the numbers of hospitalizations due to lower respiratory tract ...
Mitsuaki Hosoya   +4 more
wiley   +1 more source

Performance Evaluation of Molecular Detection of Enteroviruses: Results of 18 Years of Quality Control for Molecular Diagnostics (QCMD) External Quality Assessment Program, 2005−2022

open access: yesJournal of Medical Virology, Volume 96, Issue 12, December 2024.
ABSTRACT The gold standard for enterovirus (EV) detection is the polymerase chain reaction based on the detection of the 5' untranslated region of the virus. Correct detection of EV is crucial for patient and public health purposes. The performance of diagnostic and public health laboratories on molecular EV‐detection was analyzed using data from the ...
Kimberley S. M. Benschop   +7 more
wiley   +1 more source

Presentation_1_Zinc Influx Restricts Enterovirus D68 Replication.pdf

open access: yes, 2021
Enterovirus D68 (EV-D68) is a respiratory viral pathogen that causes severe respiratory diseases and neurologic manifestations. Since the 2014 outbreak, EV-D68 has been reported to cause severe complications worldwide.
Shunan Liu (5048615)   +3 more
core   +1 more source

Enterovirus Antibodies: Friends and Foes

open access: yesReviews in Medical Virology, Volume 34, Issue 6, November 2024.
ABSTRACT Enteroviruses (EV) initiate replication by binding to their cellular receptors, leading to the uncoating and release of the viral genome into the cytosol of the host cell. Neutralising antibodies (NAbs) binding to epitopes on enteroviral capsid proteins can inhibit this infectious process through several mechanisms of neutralisation in vitro ...
Chaldam Jespère Mbani   +6 more
wiley   +1 more source

Protective role of antibodies in enteric virus infections: Lessons from primary and secondary immune deficiencies

open access: yesImmunological Reviews, Volume 328, Issue 1, Page 243-264, November 2024.
Summary Enteric viruses are the main cause of acute gastroenteritis worldwide with a significant morbidity and mortality, especially among children and aged adults. Some enteric viruses also cause disseminated infections and severe neurological manifestations such as poliomyelitis.
Quentin Riller   +4 more
wiley   +1 more source

EV D68 5\u27UTR Structure Analysis via SHAPE-MaP

open access: yes, 2020
Enterovirus D68 is a single-stranded positive-sense RNA virus belonging to picornaviridae family. First isolated in 1962 in California, EV-D68 only had minor cases of respiratory illness associated with it until 2014.
Ojha, Pranav
core  

Differentiating EV-D68 from HRV by RVP signal of 50nA.

open access: yes, 2015
Differentiating EV-D68 from HRV by RVP signal of 50nA.
Sophie Arbefeville (708895)   +6 more
core   +1 more source

Enterovirus D68 Subgenotype B3 Circulation in Children with Acute Respiratory Illness in the State of Alagoas, Brazil

open access: yesViruses
Enterovirus D68 (EV-D68) is a leading cause of acute respiratory disease outbreaks, especially among children. EV-D68 infections can rapidly progress to severe clinical complications and potentially fatal outcomes.
Alex Ranieri Jerônimo Lima   +12 more
doaj   +1 more source

A new Real-Time RT-PCR Assay for Detection of Human Enterovirus 68 (EV-D68) in Respiratory Samples.

open access: yes, 2015
A global reemergence of human enterovirus 68 (EV-D68) associated with severe respiratory illness was occurred during the 2014. We developed and validated an EV-D68-specific real-time RT-PCR for the detection of EV-D68 in respiratory samples.
Girello A   +3 more
core   +1 more source

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