Results 81 to 90 of about 248,805 (183)

Rezafungin Utilisation in Real Life—FungiScope Results From Europe and the United States

Mycoses, Volume 68, Issue 9, September 2025.
ABSTRACT Background Rezafungin, a novel echinocandin with once‐weekly intravenous dosing, offers potential advantages for outpatient parenteral antifungal therapy (OPAT) in invasive candidiasis (IC). While clinical trial data support its efficacy and safety, real‐world experience remains limited.
Ilana Reinhold, Giovanni Mori, Massimiliano Lanzafame, Alessandro Limongelli, Antonio Vena, Julia Götz, Stilla Bauernfeind, Frank Hanses, Lukas Tometten, Michael Mayer, Ansgar Rieke, Ana Soriano‐Martin, Maricela Valerio, Jose A. Vazquez, Patrick Yue, Laman Rahimli, Nijat Azimli, Ertan Sal, Jon Salmanton‐García, Natalia Vasenda, Rosanne Sprute, Jannik Stemler, Sebastian Wingen‐Heimann, Oliver A. Cornely, Danila Seidel   +24 more
wiley   +1 more source

Understanding Enterovirus D68-Induced Neurologic Disease: A Basic Science Review

Viruses, 2019
In 2014, the United States (US) experienced an unprecedented epidemic of enterovirus D68 (EV-D68)-induced respiratory disease that was temporally associated with the emergence of acute flaccid myelitis (AFM), a paralytic disease occurring predominantly ...
Alison M. Hixon, Joshua Frost, Michael J. Rudy, Kevin Messacar, Penny Clarke, Kenneth L. Tyler   +5 more
doaj   +1 more source

The Mathematics of Serocatalytic Models With Applications to Public Health Data

Statistics in Medicine, Volume 44, Issue 15-17, July 2025.
ABSTRACT Serocatalytic models are powerful tools which can be used to infer historical infection patterns from age‐structured serological surveys. These surveys are especially useful when disease surveillance is limited and have an important role to play in providing a ground truth gauge of infection burden.
Everlyn Kamau, Junjie Chen, Sumali Bajaj, Nicolás Torres, Richard Creswell, Jaime A. Pavlich‐Mariscal, Christl Donnelly, Zulma Cucunubá, Ben Lambert   +8 more
wiley   +1 more source

Pterostilbene Exhibits Broad‐Spectrum Antiviral Activity by Targeting the Enterovirus Capsid, Inactivating Viral Particles, Blocking Viral Binding, and Protecting Mice From Lethal EV‐A71 Challenge

Phytotherapy Research, Volume 39, Issue 6, Page 2672-2688, June 2025.
Pterostilbene (Pte) binds to the VP1 hydrophobic pocket of enteroviruses, stabilizing the viral capsid and preventing uncoating and RNA release. In vitro, Pte inactivates virions and impairs viral attachment, entry, and replication. In vivo, oral administration of Pte in hSCARB2‐transgenic mice reduces clinical symptoms and improves survival ...
Kuan‐Ting Chuang, Siao‐Cian Pan, Bor‐Luen Chiang, Shih‐Hsun Chen, Min‐Hsiung Pan, Yu‐Li Chen, Cheng‐Sheng Lin, Chun‐Kai Pan, Jing‐Yi Lin, Yu‐Li Lin   +9 more
wiley   +1 more source

EV-D68 [PDF]

September 12, 2014, 17:00 ET (5:00 pm ET)CDCHAN-00369The Centers for Disease Control and Prevention (CDC) is working closely with hospitals and local and state health departments to investigate recent increases in hospitalizations of patients with severe

core   +2 more sources

Outbreak of Enterovirus D68 in Young Children, Brescia, Italy, August to November 2024

Journal of Medical Virology, Volume 97, Issue 5, May 2025.
ABSTRACT Enterovirus D68 (EV‐D68) is responsible for a plethora of clinical manifestations ranging from asymptomatic infections to severe respiratory symptoms and neurological disorders. EV‐D68 was first detected in children with pneumonia in 1962 and, from then, only sporadic cases were reported until 2014, when outbreaks were notified across the ...
Serena Messali, Anna Bertelli, Laura Dotta, Marta Giovanetti, Leonardo Sclavi, Giulia Venneri, Massimo Ciccozzi, Raffaele Badolato, Arnaldo Caruso, Francesca Caccuri   +9 more
wiley   +1 more source

Enteroviruses in Water: Epidemiology, Detection and Inactivation

Environmental Microbiology, Volume 27, Issue 5, May 2025.
In this review, enterovirus presence and persistence in water are described. The epidemiology, detection and monitoring and control of enteroviruses are discussed. ABSTRACT Enteroviruses are small non‐enveloped RNA viruses commonly found in environmental water samples.
Corentin Morvan, Magloire P. Nekoua, Chaldam J. Mbani, Cyril Debuysschere, Enagnon K. Alidjinou, Didier Hober   +5 more
wiley   +1 more source

Clinical Outcomes of Children with EV-D68 or RV/EV infections during the 2014 Outbreak.

, 2016
Clinical Outcomes of Children with EV-D68 or RV/EV infections during the 2014 Outbreak.
Amy Leber (3359129), Douglas Salamon (3359132), Huanyu Wang (332909), Asuncion Mejias (173484), Katherine Moyer (3359135)   +4 more
core   +1 more source

Enterovirus D68 circulation between 2014 and 2022 in Slovenian children

Frontiers in Virology
IntroductionEnterovirus D68 (EV-D68) belongs to the Picornaviridae family, genus Enterovirus. It is mostly known as a respiratory virus causing upper and lower respiratory tract infections, but it is also rarely associated with a variety of central ...
Tina Uršič, Monika Jevšnik Virant, Rok Kogoj, Uros Krivec, Uros Krivec, Joanna Prusnik, Minca Mramor, Sara Lovšin, Miroslav Petrovec   +8 more
doaj   +1 more source

Insights Into Enterovirus D68 Immunology: Unraveling the Mysteries of Host‐Pathogen Interactions

Immunity, Inflammation and Disease, Volume 13, Issue 2, February 2025.
This review provides a comprehensive overview of the immunological responses to Enterovirus D68, offering valuable insights for researchers, clinicians, and public health professionals working towards effective prevention and control strategies. ABSTRACT Background Enterovirus D68 (EV‐D68) has emerged as a significant respiratory and neurological ...
Asif Naeem, Muhammad Bashir Bello, Mohammad Bosaeed   +2 more
wiley   +1 more source