Results 81 to 90 of about 317,847 (188)
Bee products as alternatives in the treatment of viral infections
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
EV D68 5\u27UTR Structure Analysis via SHAPE-MaP
Enterovirus D68 is a single-stranded positive-sense RNA virus belonging to picornaviridae family. First isolated in 1962 in California, EV-D68 only had minor cases of respiratory illness associated with it until 2014.
Ojha, Pranav
core +1 more source
Mucosal Immunity: The Key to Combating Enteroviruses and Beyond
Enteroviruses (EVs) lead to 10–15 million symptomatic infections each year in the United States alone. EVs enter through either the gastrointestinal or respiratory mucosa, depending on the specific virus. Since these mucosal surfaces are the primary entry points for viruses, mucosal immunity serves as a crucial first line of defense.
Nida Kalam +2 more
wiley +1 more source
Rational design and in vivo validation of capsid inhibitors for enterovirus D68
Enterovirus D68 (EV-D68) is a respiratory virus that causes neurological complications such as acute flaccid myelitis (AFM) and death in children. No vaccine or antiviral is available for EV-D68.
Kan Li +12 more
doaj +1 more source
Enterovirus D68 circulation between 2014 and 2022 in Slovenian children
IntroductionEnterovirus D68 (EV-D68) belongs to the Picornaviridae family, genus Enterovirus. It is mostly known as a respiratory virus causing upper and lower respiratory tract infections, but it is also rarely associated with a variety of central ...
Tina Uršič +8 more
doaj +1 more source
Andrographolide Inhibits Rabies Virus Replication
Rabies is a fatal zoonotic disease caused by infection with the rabies virus (RABV). Anti‐RABV serum or antibody is a unique treatment for patients infected by RABV. However, the mortality is almost 100% in the underdeveloped regions due to the high price and the high cost of transportation and preservation of anti‐RABV serum or antibody. Therefore, it
Yue Zhang +8 more
wiley +1 more source
Enterovirus D68 (EV-D68) causes respiratory illness in children. It also causes severe paralysis called acute flaccid myelitis (AFM), which has become a global health threat. Here, we generated an mRNA vaccine expressing virus-like particles (VLPs) of EV-
Yuta Kunishima +4 more
doaj +1 more source
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro +5 more
wiley +1 more source
Enterovirus A‐71 Associated Parainfectious Movement Disorders in Children
Abstract Background Pediatric movement disorders can be challenging to characterize, given the phenotypic complexity and broad differential diagnosis. While genetic tests are often part of the diagnostic work‐up, it is important to consider acquired causes, which may require specific investigations.
Suus A. M. van Noort +6 more
wiley +1 more source
Persistence and diversification of EV-D68 since 2014.
Multiple EV-D68 lineages persist from one biennial outbreak to another. (A) Zoomed-in view of the whole genome EV-D68 tree (for better time-resolution), showing 2018 subgroups in the B3 subclade.
Emma B. Hodcroft (10204670) +13 more
core +1 more source

