Results 131 to 140 of about 32,714,285 (374)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Pharmacogenetic testing in the treatment of type 2 diabetes with sulfonylurea drugs

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The article analyses scientific literature on the use of pharmacogenetic testing to optimize sulfonylurea treatment of patients with type 2 diabetes.
G. I. Gorodetskaya   +7 more
doaj  

Money Guidance Pathfinder - A Report to the FSA [PDF]

open access: yes, 2010
In April 2009 the Government and the Financial Services Authority launched the £12m Money Guidance Pathfinder service in the North-West and North-East of England. The service, known as Moneymadeclear, provides impartial information and guidance on a wide
Collard, Sharon, Kempson, Elaine
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

FUNCTIONAL EVALUATION: THE BARTHEL INDEX.

open access: yesMaryland state medical journal, 2018
F. Mahoney, D. W. Barthel
semanticscholar   +1 more source

Meta-evaluation of the impacts and legacy of the London 2012 Olympic Games and Paralympic Games : Developing methods paper [PDF]

open access: yes, 2012
This report brings together the interim findings from the Developing Meta-Evaluation Methods study, which is being undertaken in conjunction with the Meta-Evaluation of the Impacts and Legacy of the London 2012 Olympic Games and Paralympic Games.
Gough, David, Martin, Steve
core   +1 more source

Evaluation of urban surface parameterizations in the WRF model using measurements during the Texas Air Quality Study 2006 field campaign [PDF]

open access: gold, 2011
Sang‐Hyun Lee   +8 more
openalex   +1 more source

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