Results 131 to 140 of about 17,544,570 (361)

Evaluation of Road Roughness and Road Deterioation [PDF]

open access: yes, 2013
There are two road condition survey methods commonly used, the roughness-based equipment such as NAASRA and the distress and severity type road evaluation method as presented by ASTM D-6433.
Djakfar, L. (Ludfi)   +3 more
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Ketoacidosis as unexpected adverse reaction SGLT2 inhibitor

open access: yesБезопасность и риск фармакотерапии, 2018
Inhibitors of the sodium-glucose cotransporter-2 SGLT2 is a new class of hypoglycemic drugs. This article presents the information on FDA reports (2013-2015) and AIS (May 2015 - February 2016) on the risk of new adverse reaction - ketoacidosis ...
T. M. Bukatina   +7 more
doaj  

An Evaluation of Study Methods—A Summary [PDF]

open access: bronze, 1951
Antonio Ciocco, Martha D. Ring
openalex   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Cell cultures in replacement therapy

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
Cell replacement therapy is one of the top priority areas of modern medicine, which is aimed at restoring the structure and functions of damaged tissues by transplanting cells grown in vitro .
E. M. Petruchuk   +7 more
doaj  

Analyzing the usage of theories of change for routine immunization programs -- a review of impact evaluations from LMICs

open access: yesJournal of Health, Population and Nutrition
Background In this article we analyzed the extent of the usage of Theories of Change (TOCs) and causal pathways in the evaluation of immunization programs to identify the challenges to generating evidence on how interventions improve immunization ...
Lalitha Vadrevu   +2 more
doaj   +1 more source

Evaluation of The Multiple Spot Discoloration Tester [PDF]

open access: bronze, 1955
Thomas D. Price, Hans Klemperer
openalex   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

First available biosimilar monoclonal antibodies

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
The review deals with the issues related to the special aspects of the development of the first available similar biopharmaceuticals/biological analogues («biosimilars») based on monoclonal antibodies.
Zh. I. Avdeeva   +7 more
doaj  

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