Results 141 to 150 of about 8,166,444 (292)
External review of the Pan Asia Networking Program [PDF]
, 2010 French version available in IDRC Digital Library: Constatations en bref de l'examen externe du programme Pan AsieThis findings brief is based on the reports "Pan Asia Networking (PAN) Prospectus Review 2006-2011" by the Pan Asia Networking program, and
IDRC. Evaluation Unit
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
External review of the Governance Equity and Health Program [PDF]
, 2010 French version available in IDRC Digital Library: Constatations en bref de l'examen externe du programme Gouvernance, équité et santéThis findings brief is based on two reports: the "Governance, Equity, and Health Program Final Report 2006-2011" by the
IDRC. Evaluation Unit
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Recombinant zoster vaccine is associated with a reduced risk of dementia
Nature CommunicationsVaccines to prevent herpes zoster have been associated with reduced dementia risk. We conducted a retrospective matched cohort study of Kaiser Permanente Southern California members aged ≥65 years who received two doses of RZV 4 weeks–6 months apart ...
Emily Rayens +12 more
doaj +1 more source
Pacific Island Countries Program Evaluation (FY05–15)
, 2016 This appendix is an adjunct to the main report. It is not intended as a free-standing Country Program Evaluation (CPE) on the World Bank in Tonga. It provides additional underpinning and evidence for the
Independent Evaluation Group
core
External review of Acacia Program [PDF]
, 2010 French version available in IDRC Digital Library: Constatations en bref de l'examen externe du programme ACACIAThis findings brief is based on the reports "Acacia 2006-2010 Final Report" by the Acacia Program, April 2010, and "External Review of the ...
IDRC. Evaluation Unit
core
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source