Results 131 to 140 of about 8,166,444 (292)

Pharmacogenetic testing in the treatment of type 2 diabetes with sulfonylurea drugs

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
The article analyses scientific literature on the use of pharmacogenetic testing to optimize sulfonylurea treatment of patients with type 2 diabetes.
G. I. Gorodetskaya   +7 more
doaj  

Optimal allocation of antenatal and young child nutrition interventions: an individual-based global burden of disease calibrated microsimulation

open access: yesBMC Global and Public Health
Background Undernutrition remains a global crisis and is a focus of Sustainable Development Goals. While there are multiple known, effective interventions, complex interactions between prevention and treatment and resource constraints can lead to ...
Alison Bowman   +10 more
doaj   +1 more source

Evaluation Unit report 2005-2010 [PDF]

open access: yes, 2010
This report is part of the external review of the International Development Research Centre's Evaluation Unit (EU). Centre programs undergo an external review every five years.
IDRC. Evaluation Unit
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Dances Phase 2 Evaluation Report

open access: yes, 2016
This document provides the XSEDE Technology Investigation Service evaluation of the DANCES project phase 2 evaluation of the Corsa DP6410 network device as performed by the DANCES staff at University of Tennessee Joint Institute for Computational ...
The Technology Investigation Service's Technology Evaluation Team
core   +1 more source

Findings brief : external review of the Economy and Environment Program for South East Asia [PDF]

open access: yes, 2009
French version available in IDRC Digital Library: Constatations en bref de l'examen externe du Programme d'économie environnementale pour l'Asie du Sud-EstThis findings brief is based on the report, "Evaluation of Economy and Environment Program for ...
IDRC. Evaluation Unit
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Writing Terms of Reference (ToRs) for an Evaluation [PDF]

open access: yes, 2004
French version available in IDRC Digital Library: Rédaction du mandat d ...
IDRC. Evaluation Unit
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

PROTOCOL: Interventions for improving learning outcomes and access to education in low‐ and middle‐income countries: a systematic review

open access: yesCampbell Systematic Reviews, 2017
Birte Snilstveit   +8 more
doaj   +1 more source

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